University Of Sao Paulo
Clinical trials sponsored by University Of Sao Paulo, explained in plain language.
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Gum graft showdown: own tissue vs. collagen patch – which works better?
Disease control CompletedThis study tested two methods to cover exposed tooth roots caused by receding gums. One method uses a small piece of the patient's own gum tissue (connective tissue graft), while the other uses a special collagen patch (Mucoderm). Both were combined with a surgical flap procedure…
Phase: NA • Sponsor: University of Sao Paulo • Aim: Disease control
Last updated Apr 29, 2026 06:26 UTC
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Blue dye wash may cut fluid overload after heart surgery
Disease control CompletedThis study tested a new method to reduce fluid overload and inflammation in 124 adults having heart surgery with a heart-lung machine. The approach washes the blood with methylene blue during a filtering process. Researchers measured body water levels and inflammatory markers to …
Phase: PHASE2 • Sponsor: University of Sao Paulo • Aim: Disease control
Last updated Apr 28, 2026 13:02 UTC
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Pessary or progesterone: which better prevents preterm birth?
Prevention CompletedThis study tested whether a silicone ring (pessary) placed in the vagina or natural progesterone hormone works better to prevent early delivery in pregnant women whose cervix is 25 mm or shorter. The trial included 203 women with a single baby between 20 and 24 weeks of pregnancy…
Phase: PHASE4 • Sponsor: University of Sao Paulo • Aim: Prevention
Last updated Apr 29, 2026 06:27 UTC
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Light and sound waves ease diabetic nerve damage
Symptom relief CompletedThis study tested a combination of laser and ultrasound therapy to treat early diabetic peripheral neuropathy, a nerve condition that causes pain, burning, and numbness in people with type 2 diabetes. Sixty adults aged 45 to 70 received 24 treatment sessions over 12 weeks. The re…
Phase: NA • Sponsor: University of Sao Paulo • Aim: Symptom relief
Last updated Apr 29, 2026 06:23 UTC
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Ayahuasca or esketamine: which eases depression better?
Symptom relief CompletedThis study tested whether four weekly doses of ayahuasca (a plant-based brew) or esketamine (a nasal spray) could reduce symptoms in 22 adults with severe depression. Both treatments aim to quickly improve mood, but the trial was small and early-stage. Results help guide future r…
Phase: PHASE2 • Sponsor: University of Sao Paulo • Aim: Symptom relief
Last updated Apr 28, 2026 13:02 UTC