University Of Milano Bicocca

This phase 2 trial tested the oral drug lorlatinib in 9 people with ALK-positive anaplastic large cell lymphoma whose cancer had returned or stopped responding to previous ALK inhibitors. The main goal was to see how many patients' tumors shrank or disappeared. Researchers also t…

This study tested whether adding regional citrate anticoagulation (RCA) to standard heparin can reduce clotting in continuous kidney dialysis circuits for patients on ECMO. Eighteen ICU adults with ARDS and acute kidney injury were enrolled. Each patient received alternating peri…

This study looked at whether learning to play Go or Chess can improve thinking skills in people with mild cognitive impairment or subjective cognitive decline. 80 participants were split into groups that played Go, Chess, both, or neither for 12 weeks. The researchers measured ch…

This study tested whether a mobile app could encourage healthy eating by promoting legume purchases. Researchers asked 682 adults to use the app and then complete a simulated online grocery shopping task. The goal was to see if tailored messages could increase the number of legum…

This study looked at 150 people with mild memory problems to see if a special MRI scan (pCASL) could give similar information to a standard PET scan. Participants had both scans, plus a spinal tap and yearly memory tests for three years. The goal was to see if the MRI could help …

This study examined 186 people with Alzheimer's, Lewy body, frontotemporal, or corticobasal dementia, plus healthy controls, to see if subtle physical signs (like coordination or reflexes) differ between dementia types. Participants had simple exams and cognitive tests. The goal …

This study observed how breathing machines (mechanical ventilation) are used in 2,299 brain-injured patients in intensive care units worldwide. Researchers collected data on different ventilation strategies and their link to patient recovery. No new treatments were tested; the go…

This study tested a mobile app called OASES that guides nurses and clinical officers in rural Uganda through emergency care steps for severe diarrhea, breathing problems, and seizures. About 15 clinicians used the app during simulated patient scenarios to see if it helped them fo…

Researchers used machine learning to analyze electronic health records from 700 patients with osteosarcoma or Ewing's sarcoma. The goal was to find patterns in survival and other outcomes. No new treatment was tested; instead, the study aimed to learn from existing data to potent…