University Of Leicester

This study tested whether a probiotic supplement could change gut bacteria and reduce harmful antibodies that damage kidneys in IgA nephropathy. 18 adults with the disease took probiotics for 3 months. Researchers measured changes in antibody levels and kidney function to see if …

This study tested whether a drug called mepolizumab, given after a severe COPD flare-up that required hospital care, could prevent future hospital stays or death. It involved 238 adults with eosinophilic COPD (a type with high levels of certain white blood cells). Participants re…

This study from the University of Leicester looked at 90 people who had finished rehabilitation for a torn Achilles tendon. Researchers used ultrasound imaging, strength tests, and questionnaires to see how well the tendon and calf muscles had healed. The goal was to understand w…

This study looked at how people with COPD experience physical activity. Researchers interviewed 54 participants and had them wear activity monitors to compare standard activity levels with personalized intensity measures. The goal was to better understand how to tailor activity r…

This completed study used leftover liver tissue from 36 adults who had surgery to create lab models of early infection. Researchers want to learn how bacteria and viruses first take hold in the liver, which could lead to new ways to prevent or treat serious bloodstream infections…

This study tested how easy and acceptable the P-STEP mobile app is for people with chronic conditions like asthma, COPD, heart disease, or diabetes. 178 adults in Leicester, UK used the app for 12 weeks to track their walking and get air quality updates. The main goal was to meas…

This completed study asked 140 people—including patients with chronic kidney disease, their families, healthcare professionals, and researchers—to identify the most important outcomes for self-managing the condition before dialysis is needed. Through multiple survey rounds, parti…

This study looked at 38 infants under 1 year old with congenital heart disease who needed heart surgery. The goal was to understand why some babies get brain injuries during surgery and to gather data for developing better monitoring tools. Researchers used MRI scans and blood sa…

This study looked at 17 adults with persistent atrial fibrillation (a long-lasting heart rhythm problem) to find specific areas in the heart that may keep the condition going. Researchers used special mapping to identify stable high-frequency electrical signals. The goal was to b…

This completed study followed 60 people with Achilles tendon rupture for one year. Researchers used ultrasound scans, calf strength tests, and questionnaires to track healing and daily function. The goal was to better understand recovery patterns, not to test a new treatment.