Liver tissue models could unlock secrets of deadly infections

NCT ID NCT05255042

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study used leftover liver tissue from 36 adults who had surgery to create lab models of early infection. Researchers want to learn how bacteria and viruses first take hold in the liver, which could lead to new ways to prevent or treat serious bloodstream infections. The study did not test any drugs or treatments on people.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could lead to better lab models for studying how infections start in the liver, helping develop new treatments for serious infections.

What could go wrong

This is a small, completed tissue study, not a clinical trial testing a treatment in patients. The models may not fully replicate human infection, and findings may not translate to real-world therapies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

liver disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UHL NHS Trust - Leicester General Hospital

    Leicester, LE5 4PW, United Kingdom