University Of Chicago

This study aimed to find the lowest effective dose of the prostate cancer drug abiraterone. Researchers tested if taking a lower dose less frequently (like every other day or a few times a week) worked as well as the standard daily dose. The goal was to maintain cancer control wh…

This study tested whether taking an oral pill containing specific gut bacteria (EDP1503) could improve the effectiveness of a standard immunotherapy drug (pembrolizumab) for people with advanced melanoma. It involved two groups: patients new to this type of immunotherapy and thos…

This study tested whether combining an immunotherapy drug (pembrolizumab) with mifepristone could help control advanced breast cancers that lack the HER2 marker. It involved 24 patients with either triple-negative or hormone receptor-positive breast cancer that had spread or coul…

This study tested whether the immunotherapy drug pembrolizumab could help adults with a specific type of aggressive lymphoma that had returned or not responded to prior treatments. It focused on patients whose lymphoma cells had a particular genetic change (PD-L1 alteration). The…

This study tested a new, shorter MRI scan designed to be a better and more affordable screening tool for breast cancer. It focused on women with dense breast tissue or a moderately increased risk, where standard mammograms can miss cancers. The goal was to see if this faster MRI …

This study aimed to see if giving children and teenagers with autism a supplement called glutathione by mouth for 12 weeks was safe and practical. The researchers wanted to check if it increased glutathione levels in the blood, which they thought might help reduce problem behavio…

This study compared two approaches to recovery after open-heart surgery. One group followed strict movement restrictions (like not lifting over 5-8 pounds). The other group was told to let their pain and discomfort guide their activity. Researchers wanted to see if the more flexi…

This study aimed to find out if using skeletal traction (a system of weights and pulleys) on a broken thigh bone before surgery makes the operation faster or easier. Researchers compared surgery time, pain medication needs, and blood loss between patients who received traction an…

This study aimed to discover if Hidradenitis Suppurativa (HS), a chronic and painful skin condition, is passed down in families through specific genes. Researchers collected DNA and family history from 97 participants, including people with HS and their unaffected relatives, to l…

This study aims to understand why some multiple myeloma patients experience shortness of breath when taking the cancer drug carfilzomib. Researchers will use a special device to measure blood vessel health in 50 patients receiving this treatment. The goal is to identify risk fact…