University Hospital, Antwerp

This early-phase trial is testing whether adding an immunotherapy drug (atezolizumab) and a personalized vaccine (WT1/DC) to standard chemotherapy can safely improve outcomes for people with a rare type of mesothelioma. The study plans to enroll 15 adults with epithelioid maligna…

This study looks at whether a structured program to find and treat obstructive sleep apnea can reduce the amount of time people with atrial fibrillation have an irregular heartbeat. About 209 adults with AF will use a home sleep test device and a Fitbit smartwatch to track their …

This study tests whether a special activity score, calculated from heart rate data, can help people who have completed cardiac rehab stick to exercise guidelines. About 318 participants will wear a smartwatch for 4 months and do an exercise test at the end. Researchers will compa…

This study tests whether adding the CytoSorb blood-filtering device to standard hospital care can better remove waste products like bilirubin and ammonia in people with sudden worsening of chronic liver disease. Twenty adults with severe liver failure will receive the device for …

This study compares two types of cornea transplant surgery—DSAEK and DMEK—in 220 adults with corneal swelling or Fuchs' dystrophy. The goal is to see which procedure leads to better vision and patient satisfaction one year after surgery. Participants will be randomly assigned to …

This study tests whether using lower-salt intravenous fluids in ICU patients reduces the number of days they need life support like ventilators or dialysis. Researchers will compare a salt-free glucose solution for medication dilution and a low-salt maintenance fluid against the …

This registry follows 225 adults with moderate-to-severe obstructive sleep apnea who receive the Inspire hypoglossal nerve stimulation implant. The device is for people who cannot use CPAP, the standard treatment. Researchers will measure how well it reduces breathing pauses duri…

This study is testing a new blood test called the T-cell activation test to see if it can more accurately diagnose amoxicillin allergy. Researchers will compare results from 300 people with suspected allergy and those without. If the test works well, it could replace less reliabl…

This study is testing a new, non-invasive ultrasound device called the Hepatoscope to screen for liver scarring (fibrosis) and fatty liver in people at risk. Researchers will enroll 200 patients with risk factors like diabetes or elevated liver enzymes. Those with high stiffness …

This study looks at whether a special type of exercise called eccentric training (where muscles lengthen under tension) can help people with heart failure and reduced pumping ability. Researchers will compare eccentric bike and strength training to standard cardio and strength ex…

This study is testing a mobile app called Cardio2U for people with atrial fibrillation or heart failure. The app helps patients track their condition, learn about their disease, and communicate with their care team. Researchers will check if patients find the app easy to use and …

This study will test new methods to measure how sleep apnea affects the heart. Researchers will follow 270 adults with moderate to severe sleep apnea who use CPAP, mouth devices, or nerve stimulation. The goal is to see if these new metrics can better predict heart problems than …

This study looks at whether a simple saliva test can find people at high risk for lung cancer more accurately than asking about their smoking history. Researchers will collect saliva from about 1,000 adults aged 50-74 and check for DNA changes linked to smoking. The goal is to cr…

This study tests whether patients with serious infections who are at risk for sepsis can be safely monitored at home using wearable devices and a smartphone app. About 120 adults will take part, and the goal is to see if this approach can reduce hospital visits while still catchi…

This study looks at how common muscle loss and weakness are in people with liver cirrhosis, and how malnutrition plays a role. Researchers will use ultrasound to measure muscle size and a grip test to check strength. The goal is to better understand the problem and its impact on …

This study is testing whether using a blood test (liquid biopsy) to monitor treatment response can help people with advanced colorectal cancer maintain a better quality of life. Instead of relying only on CT scans, doctors will use the blood test to adjust treatment earlier and m…

This study talks one-on-one with 30 adults who are anxious about their upcoming elective surgery. The goal is to learn exactly what worries them, so doctors can create better support plans and possibly prevent long-term pain after the operation. Participants will answer questions…

This study looks at 160 children with protracted bacterial bronchitis (PBB), a condition causing long-term cough. Researchers will analyze samples from the children's airways to understand the mix of bacteria and viruses, how the immune system responds, and how the standard antib…

This pilot study is testing whether cells collected by brushing the esophagus during a routine endoscopy can be genetically analyzed to better predict cancer risk in people with Barrett's esophagus. Researchers will collect brush samples, biopsies, and blood from 50 patients, the…

This study is observing 400 children in intensive care who need a breathing tube. Researchers want to see if the amount of air leaking around the tube can predict stridor (noisy, difficult breathing) after the tube is removed. The goal is to better understand and potentially prev…

This study follows 100 adults with rectal cancer for 2 years after surgery to see how bowel function changes over time. Researchers will compare different treatment plans to find out which ones lead to better bowel control and quality of life. The goal is to help doctors and pati…

This study reviews medical records of 200 children with obstructive sleep apnea who had tonsil surgery. Researchers want to find out how often breathing problems happen after surgery, especially in children with obesity, Down syndrome, or other health issues. The goal is to bette…

This study looks at how a device that stimulates the nerve to the tongue (hypoglossal nerve) changes the way the upper airway collapses during sleep in people with obstructive sleep apnea. Researchers will use a sleep endoscopy and sleep study data to compare collapse patterns be…

This study compares two ways of adjusting a nerve stimulator implant (Inspire system) for obstructive sleep apnea. Currently, patients need an overnight sleep study to fine-tune the device. Researchers want to see if a daytime sleep study works just as well. The trial will enroll…

This study aims to understand where the vaginal microbiome comes from and how it is passed between people. Researchers will recruit 500 participants in Belgium, including women and their close contacts, to provide swabs and samples over five years. The goal is to learn how these …