University Hospital, Angers

This study looks back at 90 children treated for pilonidal sinus disease to see which surgical technique works best. The goal is to find a method that leads to complete healing with fewer complications and lower chance of the problem coming back. Results will help doctors choose …

This early study tests whether high-dose nicotinamide (vitamin B3) can protect or improve vision in people with Leber's hereditary optic neuropathy (LHON), a rare genetic disease that causes sudden vision loss. Researchers will give 13 participants 2 grams of nicotinamide daily f…

This study looks at different surgical techniques for treating Hirschsprung disease, a rare condition where part of the colon lacks nerve cells, causing blockages. Researchers will compare a newer single-port laparoscopic method with traditional approaches in 70 children under 16…

This study tests a simple 10-item checklist that parents can complete with a doctor during a video call to help diagnose appendicitis in children aged 3 to 16. The checklist is designed to work without a physical exam, using artificial intelligence to predict the likelihood of ap…

This study tests whether a short, personalized talk with an advanced practice nurse in the pediatric emergency room can help parents of babies 0-6 months follow safe sleep recommendations. About 100 parents will be interviewed, and the study will check if more babies are placed o…

This study looks at how different levels of breathing support (PEEP) affect blood flow congestion in the veins of patients with acute respiratory distress syndrome (ARDS). Researchers will use ultrasound to check vein congestion in the liver, kidneys, and portal system at high an…

This study looks at whether changing the tubing that delivers medicine through a central line every 7 days is as safe as changing it every 4 days for ICU patients. About 2,830 adults in intensive care will take part. The goal is to see if the longer interval leads to more infecti…

This study looks at how certain thinking skills—like impulse control, planning, and adapting to change—relate to suicidal thoughts and actions in teenagers. Researchers will test 100 adolescents aged 11 to 16 who are hospitalized for suicidal behavior. The goal is to better under…

This study looks at how Huntington's disease affects a person's ability to remember their own life events and imagine future ones. Researchers will use eye-tracking and memory tests in 80 participants (patients and healthy volunteers) to find patterns that could lead to better di…

This study looks at whether dangerous blood clots in the lungs (pulmonary embolism) are often missed in patients hospitalized with acute heart failure. Both conditions cause similar symptoms like sudden shortness of breath, so doctors may not always test for a clot. Researchers w…

This study looks at bile duct and pancreas problems that can happen years after surgery for a blocked duodenum at birth. Researchers will review medical records of 450 children treated in France over the past 20 years. The goal is to find out how often these complications occur a…