University College, London

This early-phase trial tests a new treatment called GD2 CAR T cells in 12 children and teens (ages 1-16) with neuroblastoma that has come back or not responded to standard therapy. The treatment involves taking a patient's own immune cells, modifying them in a lab to better recog…

This study looks at whether low-risk thyroid cancer patients need radioactive iodine treatment after having their thyroid removed. About 500 patients are being followed to see if skipping this treatment affects cancer recurrence or survival. The goal is to find out if we can safe…

This study tests whether giving the antibiotic ciprofloxacin daily can prevent bacterial infections in children (ages 1-17) being treated for acute lymphoblastic leukemia. About 313 children in the UK will either receive ciprofloxacin or standard care during the first month of ch…

This study tests whether advanced MRI scans can tell the difference between aggressive and harmless kidney tumors before surgery. Currently, standard scans show tumor size but not type, and biopsies are invasive. Researchers will compare MRI results with tissue removed during sur…

This study tests a program called Social Prescribing for teens who feel lonely. Instead of a doctor, a school-based 'Link Worker' helps them find local activities and support groups. About 215 students from 30 English schools will either get this program or just a list of resourc…

This study looks at whether people with memory problems will wear and use digital devices like smartwatches, sleep headbands, and smartphone apps to collect health data. Researchers will combine this data with routine clinic information to build machine learning models that might…