University College, London

This study tests whether two heart failure medications, dapagliflozin and spironolactone, can help the heart recover more fully after aortic valve replacement. About 445 adults with severe aortic stenosis will take one or both drugs daily for 12 months. The goal is to reduce hear…

This study looks at 50 adults with a detached retina (a serious eye condition) to find out who might develop a complication called PVR after surgery. Researchers will collect a small sample of eye fluid during the standard surgery and take extra eye scans before and after. The go…

This study looks at whether adding a 'social prescription'—connecting young people to community activities like art, sports, or volunteering—can improve mental health for teens already receiving therapy. About 120 young people aged 11-18 will either get a link worker to help them…