Engineered immune cells take on childhood cancer in early trial

NCT ID NCT05990751

First seen Apr 25, 2026 · Last updated May 15, 2026 · Updated 4 times

Summary

This early-phase trial tests a new treatment called GD2 CAR T cells in 12 children and teens (ages 1-16) with neuroblastoma that has come back or not responded to standard therapy. The treatment involves taking a patient's own immune cells, modifying them in a lab to better recognize and attack cancer cells, and giving them back. The main goals are to see if the cells can be made safely and to check for serious side effects.

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Contacts and locations

Locations

  • Great Ormond Street Hospital

    London, United Kingdom

Conditions

Explore the condition pages connected to this study.