University Children's Hospital, Zurich

This study looks at two different surgical methods for removing simple ovarian cysts in girls and teens. The goal is to find out which technique better preserves the ovary's egg supply and lowers the chance of the cyst coming back. About 80 participants aged 1 to 18 with cysts 4 …

This study tests a new material called NovoSorb BTM for treating deep skin wounds that need a skin graft. Researchers will compare it to the usual treatment in 42 people aged 1 to 75. They will check how elastic and healthy the healed skin looks after one year.

This study aims to develop a better blood test for early Lyme disease in children. Current tests often miss early infections or give false positives. Researchers will also study the immune response and the types of Lyme bacteria involved. About 500 children with suspected Lyme di…

This study is testing a new way to measure how well the urea cycle works in healthy people and in patients with urea cycle disorders (UCDs). Participants receive a safe, non-radioactive tracer, and blood samples are taken over a few hours. The goal is to develop a better tool for…

This study tests whether a short-arm fiberglass cast works as well as a long-arm cast for stabilizing certain forearm fractures in children aged 4 to 16. The goal is to see if the shorter cast provides enough support while being more comfortable. About 120 children with Salter Ha…

This study looks at children with congenital melanocytic nevi (large birthmarks) who choose to have them surgically removed. Researchers want to see if removal improves quality of life and reduces feelings of being stigmatized. About 100 children aged 9 months to 16 years will be…

This study aims to find new genetic causes of primary immunodeficiency, a condition where the immune system doesn't work properly, leading to frequent or severe infections. Researchers will compare the genes of 500 people with suspected immunodeficiency, their relatives, and heal…

This study follows 21 adolescents aged 12 to 18 who have experienced trauma and are undergoing trauma-focused cognitive behavioral therapy (TF-CBT). Researchers will regularly measure their PTSD symptoms, along with anxiety and depression, to see how symptoms change over time. Th…

This study is testing a new questionnaire called PTSD-iMPACT to see how well it measures the ways PTSD can interfere with daily life in children and adolescents. Researchers will include 1,200 participants from Switzerland and Germany, both those with and without PTSD symptoms. T…