University Children's Hospital, Zurich

This study tests a new dermal substitute called NovoSorb BTM for treating deep skin defects from burns, injuries, or surgery. Researchers will compare skin elasticity and quality of life in 42 participants aged 1 to 75 years who receive the new substitute versus standard care. Th…

This study looks at a new way to diagnose Lyme disease in children earlier and more accurately. Current tests can miss early infections or give false positives. The new method measures specific immune cells that appear soon after infection. Researchers will study up to 502 childr…

This study looks at whether a short-arm cast works as well as a long-arm cast for children with certain forearm fractures (Salter-Harris I/II). About 120 kids aged 4 to 16 will be randomly assigned to one of the two cast types. The goal is to see if the shorter cast keeps the bon…

This study looks at children with large birthmarks (congenital melanocytic nevi) who choose to have them surgically removed. The goal is to see if removal improves their quality of life and reduces feelings of being stigmatized. About 100 children aged 9 months to 16 years will b…

This observational study follows 21 adolescents aged 12-18 with post-traumatic stress symptoms to see how their symptoms change during trauma-focused cognitive behavioral therapy (TF-CBT). Researchers use a personalized questionnaire to track each teen's most distressing symptoms…

This study aims to find new genetic causes for primary immunodeficiency, a condition where the immune system doesn't work properly. Researchers will compare the genes of 500 people with suspected immunodeficiency, their relatives, and healthy volunteers. The goal is to better und…

This study is testing a new questionnaire called PTSD-iMPACT to see how well it measures the ways PTSD affects children's and teens' daily functioning at home, school, with friends, and in hobbies. Researchers will ask 1,200 young people and their caregivers in Switzerland and Ge…

This study looks at two different surgical methods for removing simple ovarian cysts in girls and teenagers. The goal is to find out which technique better protects the ovary's egg supply and lowers the chance of the cyst coming back. About 80 participants aged 1 to 18 with cysts…

This study aims to measure how well the body produces urea in healthy people and in those with urea cycle disorders (UCDs). Researchers will use a safe, non-radioactive tracer to track urea production from blood samples. The goal is to develop a better way to test the effectivene…