Simple test could unlock better monitoring for rare metabolic disorders

NCT ID NCT05671666

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing a new way to measure how well the urea cycle works in healthy people and in patients with urea cycle disorders (UCDs). Participants receive a safe, non-radioactive tracer, and blood samples are taken over a few hours. The goal is to develop a better tool for evaluating current and future treatments for UCDs.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
stable ammonium chloride isotope tracer
What this could lead to
If successful, this test could provide a better way to measure how well the urea cycle works, helping to evaluate new treatments for urea cycle disorders.
What could go wrong
This is an early diagnostic study, not a treatment trial. The test may not prove useful for all patients or may not be widely adopted.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University Children's Hospital

    RECRUITING

    Zurich, Canton of Zurich, 8008, Switzerland

More trials for these conditions

Other studies related to the condition(s) this trial covers.