Umc Utrecht
Clinical trials sponsored by Umc Utrecht, explained in plain language.
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Stem cell showdown: can a transplant beat meds for scleroderma?
Disease control CompletedThis study compared two treatment strategies for people with early, severe scleroderma (a rare autoimmune disease that causes skin thickening and organ damage). One group received a stem cell transplant right away, while the other group started with standard immunosuppressive dru…
Phase: PHASE4 • Sponsor: UMC Utrecht • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Could a special putty replace bone grafts for cleft repair?
Disease control CompletedThis study tested a new ceramic putty to repair bone gaps in the gums of 84 children with cleft lip and palate. The putty aims to help new bone grow without needing to take bone from the child's own jaw. Researchers compared the amount of new bone formed one year after surgery us…
Phase: NA • Sponsor: UMC Utrecht • Aim: Disease control
Last updated May 13, 2026 16:03 UTC
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Artificial pancreas breakthrough: dual hormone system could transform diabetes care
Disease control CompletedThis study tested a fully automated system that delivers both insulin and glucagon to manage blood sugar in adults with type 1 diabetes. Over 12 months, 243 participants used the dual-hormone closed loop system or standard care. The goal was to see if the system helps people spen…
Phase: NA • Sponsor: UMC Utrecht • Aim: Disease control
Last updated May 11, 2026 20:47 UTC
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New Pre-Surgery step may reduce leaks in esophageal cancer operations
Disease control CompletedThis study tested a two-step surgery approach for 22 people with esophageal cancer who had hardened arteries, which raises the risk of leaks after the main surgery. First, doctors performed a keyhole procedure to prepare the stomach by improving its blood supply. About two weeks …
Phase: NA • Sponsor: UMC Utrecht • Aim: Disease control
Last updated Apr 30, 2026 15:50 UTC
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Keyhole surgery for stomach cancer may get you home sooner
Symptom relief CompletedThis study compared two surgical methods for stomach cancer: laparoscopic (keyhole) surgery and open surgery. The goal was to see if keyhole surgery leads to a shorter hospital stay and fewer complications. 210 adults with resectable stomach cancer took part. Results will help do…
Phase: NA • Sponsor: UMC Utrecht • Aim: Symptom relief
Last updated May 15, 2026 11:56 UTC
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New imaging tool may spot chemo damage early
Knowledge-focused CompletedThis completed study tested whether a non-invasive MRI technique (31P-MRS) can monitor changes in energy production in the heart and calf muscles of cancer patients receiving chemotherapy with anthracyclines or platinum drugs. Twelve adult cancer patients underwent three imaging …
Sponsor: UMC Utrecht • Aim: Knowledge-focused
Last updated May 16, 2026 23:50 UTC
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Brain implant gives voice to the locked-in
Knowledge-focused CompletedThis study tested a new brain implant that lets people with locked-in syndrome communicate by using their brain signals to control a computer. Six participants tried the device at home. The goal was to see if they could reliably spell sentences and how satisfied they were with th…
Phase: NA • Sponsor: UMC Utrecht • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC