Tianjin Medical University Second Hospital

This study tests an experimental drug called tunlametinib in 15 adults with advanced solid tumors that have a specific change in the NRAS gene and have not responded to other treatments. The goal is to see if the drug can shrink tumors or slow cancer growth. Participants will tak…

This study tests two drugs (tislelizumab and disitamab vedotin) given before surgery to people with a rare, aggressive kidney cancer called HER2-positive high-risk upper tract urothelial carcinoma. The goal is to see if the combination can shrink or eliminate the tumor, making su…

This study tests a combination of two drugs (tislelizumab and nab-paclitaxel) to treat renal pelvic cancer while trying to save the kidney. About 35 adults with early-stage cancer that hasn't spread will receive the drugs, and if the tumor shrinks enough, they may get additional …

This study looks at whether removing nearby lymph nodes during standard surgery for high-risk upper tract urinary cancer helps patients live longer without the cancer returning. About 150 adults will be randomly assigned to get either the standard surgery alone or the standard su…

This study tests a three-part treatment for people with advanced kidney cancer. First, doctors block the tumor's blood supply. Then, patients receive two drugs (toripalimab and axitinib) for several months before surgery. After surgery, they continue one drug for a year. The goal…

This study tests whether a urine DNA test can help guide when to stop immunotherapy in people with a very high-risk type of bladder cancer that cannot be fully removed by surgery. About 53 participants will receive immunotherapy and then be monitored with urine tests and scans. I…

This study looks at whether a urine test that detects tumor DNA and RNA can guide doctors in deciding which patients with high-risk non-muscle-invasive bladder cancer truly need a second surgery. Currently, many patients undergo a repeat procedure, but it may not benefit everyone…

This study looks at whether a simple urine test for tumor DNA can tell which bladder cancer patients truly need a second surgery after their first tumor removal. About 196 adults with non-muscle-invasive bladder cancer will be randomly assigned to have their repeat surgery decisi…

This study is testing whether a urine DNA test can help decide when high-risk bladder cancer patients need a cystoscopy (a camera exam inside the bladder). Cystoscopy is uncomfortable and can cause side effects, but it's the standard way to check for cancer return. The urine test…