New drug combo aims to save kidneys in pelvic cancer patients

NCT ID NCT07233252

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase II trial tests whether a combination of tislelizumab (an immunotherapy) and nab-paclitaxel (a chemotherapy drug) can treat renal pelvic cancer while allowing patients to keep their kidney. About 35 adults with early-stage cancer will receive the drugs, and if the tumor shrinks enough, they may also get laser or freezing treatment to remove any remaining cancer. The main goal is to see if patients can avoid kidney removal for at least one year.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tislelizumab and nab-paclitaxel

What this could lead to

If successful, this could offer a way to treat renal pelvic cancer without removing the kidney, preserving kidney function.

What could go wrong

This is a small, early-phase trial with only 35 participants, so results may not apply widely. The combination therapy may cause side effects, and not all patients will respond well.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

renal pelvis carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Second Hospital of Tianjin Medical University

    RECRUITING

    Tianjin, Outside U.S., 300211, China

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••