Urine test may spare bladder cancer patients from unnecessary second surgery

NCT ID NCT07187635

Recruiting now Diagnosis Sponsor: Tianjin Medical University Second Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This study looks at whether a simple urine test for tumor DNA can tell which bladder cancer patients truly need a second surgery after their first tumor removal. About 196 adults with non-muscle-invasive bladder cancer will be randomly assigned to have their repeat surgery decision guided by the urine test or by standard care. The goal is to avoid unnecessary surgeries and their risks while keeping cancer control safe.

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Conditions

The condition(s) this trial relates to.

non-invasive bladder urothelial carcinoma superficial urinary bladder carcinoma urinary bladder carcinoma Urinary Bladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BLADDER CANCER LIQUID BIOPSY REPEAT TRANSURETHRAL RESECTION OF BLADDER TUMOR

Contacts and locations

Locations

General Hospital of Tianjin Medical University
RECRUITING

Tianjin, China
Nanchang Second People's Hospital
RECRUITING

Nanchang, Anhui, China
Renji Hospital
RECRUITING

Shanghai, China
Sun Yat-sen Memorial Hospital of Sun Yat-sen University
RECRUITING

Guangzhou, Guangdong, China
The Second Affiliated Hospital of Kunming Medical University
RECRUITING

Kunming, Yunnan, China
The Second Hospital of Tianjin Medical University
RECRUITING

Tianjin, 300000, China
Xingtai People's Hospital
RECRUITING

Xingtai, Hebei, China

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