The First Affiliated Hospital Of Soochow University

This study tests a new combination of three drugs (venetoclax, azacitidine, and mitoxantrone liposome) against the standard two-drug therapy for adults newly diagnosed with acute myeloid leukemia (AML). About 204 participants aged 18-65 will be randomly assigned to one of the two…

This study tests a new combination of drugs for women with ovarian cancer that has come back but still responds to platinum chemotherapy. The treatment includes an immunotherapy (iparomlimab/tuvonralimab) plus standard chemo, followed by a maintenance drug (olaparib). The goal is…

This study tests whether adding two drugs (SHR2554 and azacitidine) to standard chemotherapy before a stem cell transplant can lower the chance of leukemia returning. It includes 160 people aged 15-60 with high-risk or hard-to-treat acute leukemia or myelodysplastic syndrome. Par…

This study tests a combination of two or three drugs (Bcl-2 inhibitor, azacitidine, and possibly blinatumomab) in people newly diagnosed with a rare and aggressive leukemia called mixed phenotype acute leukemia (MPAL). The goal is to see if this treatment can lead to complete rem…

This study tests a new treatment plan for young adults and adults with B-cell acute lymphoblastic leukemia (B-ALL). The approach uses immunotherapy before an autologous stem cell transplant, followed by a 'sandwich' of two types of CAR-T cells (CD22 and CD19) to try to prevent th…

This study tests whether a combination of venetoclax and azacitidine works better than standard chemotherapy as a short-term treatment before a stem cell transplant in adults with high-risk acute myeloid leukemia (AML) who are already in remission. About 216 participants will be …