The First Affiliated Hospital Of Soochow University

This study tests a treatment using a patient's own immune cells, modified to find and attack cancer cells that carry a marker called CD19. It is for people with B-cell acute lymphoblastic leukemia that has not responded to standard treatments or has come back. The goal is to see …

This study aimed to test a new CAR-T cell therapy that targets a protein called Igβ on cancer cells in patients with relapsed or refractory B-cell non-Hodgkin's lymphoma. The trial planned to enroll patients who had already tried at least two other treatments. However, the study …

This study tests a new treatment for people with a type of blood cancer called diffuse large B-cell lymphoma that has come back or not responded to prior therapy. The treatment combines two drugs (tafasitamab and lenalidomide) with standard chemotherapy, followed by a stem cell t…

This study tests whether fecal microbiota transplantation (FMT) is safe and helpful for people with severe gut inflammation caused by stem cell transplants. About 20 patients with transplant-related gastrointestinal mucositis will receive FMT. Researchers will track when and how …

This phase 2 trial tests a new treatment plan for teenagers and adults with B-cell acute lymphoblastic leukemia. Patients receive immunotherapy before a stem cell transplant using their own cells, followed by a CD22/CD19 CAR-T 'sandwich' to reduce the risk of relapse. The study a…

This study tests a new treatment plan for adults with B-cell acute lymphoblastic leukemia (B-ALL) who cannot or choose not to have a donor stem cell transplant. The approach uses a 'sandwich' strategy: first, patients receive two types of CAR T-cells (targeting CD22 and CD19), th…

This study tests a new treatment for adults with a specific type of leukemia (Philadelphia chromosome-positive B-ALL). The treatment uses a patient's own immune cells that are modified in a lab to find and attack cancer cells. The goal is to see if this approach is safe and can h…

This phase 2 trial tests a combination of chidamide, azacytidine, and a chemotherapy regimen (HAG) in 21 adults with acute myeloid leukemia that has come back or not responded to treatment. The goal is to see how well the combo works and what side effects it causes. Participants …

This study tests whether giving patients with high-risk multiple myeloma specially engineered T-cells (CAR T-cells) after a stem cell transplant can safely improve outcomes. The T-cells are designed to target two proteins on myeloma cells, CD19 and BCMA. Researchers are monitorin…

This study tests whether N-acetylcysteine (NAC), a common antioxidant, can treat a severe blood vessel condition called TA-TMA that can happen after a stem cell transplant. Current treatments are either ineffective or very expensive. The trial will enroll 44 adults diagnosed with…

This study is testing a new way to create tumor-reactive T cells for people with non-small cell lung cancer. Researchers use a nanovaccine made from lung cancer antigens to train T cells to attack the cancer. The goal is to see if these T cells can effectively target tumors in la…

This study tests a new PET/CT imaging method that uses a radioactive peptide to find a protein called Nectin-4 on solid tumors. Researchers will scan 10 people with cancers like breast or bladder cancer that have high Nectin-4 levels. The goal is to see if this scan can show wher…

This study follows 300 people with persistent low blood cell counts (cytopenia) who do not yet have myelodysplastic syndromes (MDS), a type of blood cancer. Researchers aim to track how often these pre-MDS conditions (called ICUS and CCUS) progress to MDS. Participants receive on…