New cocktail aims to tame Slow-Growing blood cancers

NCT ID NCT07609446

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This Phase II trial will test a combination of pomalidomide, an anti-CD20 antibody, and prednisone as a first treatment for people with indolent (slow-growing) B-cell lymphomas. About 30 adults who have not had prior therapy will receive six cycles of the combo, followed by two years of maintenance. The main goal is to see how many patients respond, while also tracking side effects and how long the benefit lasts.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Pomalidomide, anti-CD20 antibody (a targeted immune therapy), and prednisone (a steroid)

What this could lead to

If successful, this could offer a new first-line treatment option for indolent B-cell lymphoma that may improve response rates and delay disease progression.

What could go wrong

This is a small, early-phase (Phase II) trial with only 30 participants, so results may not apply broadly. The combination may cause side effects like low blood counts or infections, and it is not a cure—patients will need ongoing maintenance therapy.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic lymphocytic leukemia/small lymphocytic lymphoma follicular lymphoma indolent B-cell non-Hodgkin lymphoma Lymphoma, B-Cell, Marginal Zone lymphoplasmacytic lymphoma mantle cell lymphoma marginal zone lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The First Affiliated Hospital of Soochow University

    Suzhou, Jiangsu, 215000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••