Tang-du Hospital

This phase 2 trial is testing whether giving the immunotherapy drug penpulimab together with chemotherapy before surgery can help people with locally advanced hypopharyngeal carcinoma, a type of head and neck cancer. The study will include about 15 adults aged 18 to 80 with resec…

This study tests whether adding an experimental drug called retlirafusp alfa to standard chemotherapy can shrink advanced stomach or gastroesophageal junction cancers enough to allow complete surgical removal. Participants receive the drug combination before surgery, and those wh…

This study looks at how the oral medication etrasimod works for Chinese adults with active ulcerative colitis (UC) in real-world settings. About 500 participants will take etrasimod as part of their routine care and be followed for at least 52 weeks. Researchers will track change…

This trial tests whether a standardized nursing care pathway, guided by the Bristol Stool Form Scale, can reduce the severity of diarrhea in critically ill patients receiving tube feeding. The pathway involves regular stool assessments and step-by-step interventions such as adjus…

This study tests whether a short course of radiation followed by the immunotherapy drug tislelizumab plus chemotherapy can improve outcomes for people with a type of esophageal cancer that can be surgically removed. About 50 participants will receive either a low or high dose of …

This phase II trial is testing a three-drug combination given before surgery for people with intermediate-to-high risk HR-positive, HER2-low breast cancer. Participants first take dalpiciclib (a pill) plus an aromatase inhibitor (another pill) for about 4 months, followed by infu…

This study tests whether adding a new drug called retlirafusp alfa to standard chemotherapy before surgery can help shrink tumors in people with a type of esophageal cancer. About 33 adults with locally advanced esophageal squamous cell carcinoma will receive the combination trea…

This study tests a combination of two immune-boosting drugs (iparomlimab and tuvonralimab) plus chemotherapy given before surgery for people with a specific type of advanced lung cancer (stage III-N2b non-small cell lung cancer). The goal is to see if this treatment can completel…

This study tests whether giving two drugs (vibecortamab and putilimab) before surgery can help shrink tumors in people with locally advanced laryngeal cancer. About 10 adults aged 18-80 with resectable cancer will receive the combination, then have surgery. The main goal is to se…

This study tests whether adding the immunotherapy drug toripalimab to standard chemotherapy before surgery can improve outcomes for people with resectable locally advanced esophageal squamous cell carcinoma. About 390 participants will be randomly assigned to receive either torip…

This study tests whether a simple blood test measuring miRNA levels can predict the best time to transfer an embryo during IVF. About 546 women with unexplained recurrent implantation failure will be randomly assigned to either standard embryo transfer or transfer timed based on …

This early study tests the safety of a 7-day intravenous drip of propranolol (a drug usually used for heart conditions) to prevent pneumonia in 30 adults who have had a severe brain bleed. The goal is to find the best dose and see if it reduces lung infections. Participants must …

This trial investigates whether the drug crisugabalin can reduce neuropathic pain in people with neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune condition affecting the nerves. Participants will receive either crisugabalin or a placebo, and their pain levels wil…

This study tests whether taking coenzyme Q10 before IVF can improve egg quality and pregnancy outcomes in women who produce few eggs. About 128 women with poor ovarian response will be randomly assigned to receive Q10 or a placebo. The goal is to see if Q10 increases the number o…

This study compares two types of anesthesia for early-stage lung cancer surgery: one that lets patients breathe on their own and one that uses a breathing tube. Researchers want to see which method leads to a shorter hospital stay and less pain medication use. The study will incl…