New drug duo aims to shrink throat tumors before surgery

NCT ID NCT07538206

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving two drugs (vibecortamab and putilimab) before surgery can help shrink tumors in people with locally advanced laryngeal cancer. About 10 adults aged 18-80 with resectable cancer will receive the combination, then have surgery. The main goal is to see how many patients have no cancer cells left in the removed tissue (complete response).

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms laryngeal carcinoma Pathologic Complete Response

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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