HEAD & NECK CANCER

This study is for people with advanced head and neck cancer who cannot receive standard platinum-based chemotherapy. It compares standard radiation therapy alone to radiation combined with a targeted drug called nimotuzumab. The goal is to see if adding nimotuzumab helps control …

This study is testing a combination of two immunotherapy drugs and chemotherapy given before surgery for advanced tonsil cancer. The goal is to see if this approach can shrink tumors more effectively, potentially leading to better surgical outcomes and longer survival. The study …

This study is testing a new antibody drug called OM-RCA-01 in people with advanced cancers that have spread and have a specific protein (FGFR1). The main goals are to find a safe dose and see if the drug can slow down tumor growth. About 58 people with certain types of metastatic…

This early-stage study is testing a new drug called RiMO-301, which is injected directly into tumors. It is being combined with a short, intense course of radiation and standard immunotherapy drugs (pembrolizumab or nivolumab) for people with advanced head and neck cancer that ca…

This study is testing a weekly combination of chemotherapy and immunotherapy for people with advanced head and neck cancer that has spread and who cannot take a standard chemotherapy drug called 5-FU. The goal is to see if this weekly schedule helps shrink tumors and control the …

This early-stage study is testing whether directly injecting an experimental treatment called VLPONC-01 into head and neck tumors is safe and can help shrink them. Researchers are enrolling 41 patients with advanced or surgically removable cancers to receive the injections, somet…

This study is testing a new type of imaging scan called micro-PET-CT to see if it can help surgeons during head and neck cancer surgery. The goal is to check if the scan can accurately show whether any cancer cells remain at the edges of the removed tissue, which could help surge…

This study is testing a new, non-radioactive method to find the first lymph nodes where cancer might spread. It compares a special contrast-enhanced ultrasound to the current standard method that uses a radioactive dye. The goal is to see if the ultrasound method works just as we…

This study is testing a new, non-surgical procedure to relieve severe pain in people with head, neck, or shoulder cancer. The procedure uses focused sound waves, guided by an MRI, to target a tiny area in the brain involved in pain signaling. Researchers want to see if this is sa…

This study aims to learn if a PET scan taken six weeks after starting immunotherapy can predict how well the treatment will work months later for people with advanced head and neck cancer. Researchers will observe 25 patients receiving standard pembrolizumab treatment and track t…

This study is a survey asking patients with head and neck cancer and their dentists about their knowledge and experiences with dental care. Participants answer questions online, read educational materials, and then answer the same questions again. The goal is to see if providing …