Promising cocktail aims to shrink tonsil tumors before surgery
NCT ID NCT07353723
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study is testing whether a combination of two targeted drugs (nimotuzumab and toripalimab) plus standard chemotherapy can shrink locally advanced tonsillar cancer before surgery. Ten adults with resectable tumors will receive the treatment for 2-4 cycles, then have surgery. The main goal is to see if the cancer disappears completely by the time of surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
nimotuzumab, toripalimab, nab-paclitaxel, and carboplatin
What this could lead to
If successful, this could point toward a more effective pre-surgery treatment for tonsillar cancer, potentially improving outcomes.
What could go wrong
This is a very small early-phase study with only 10 people, so results may not apply broadly. The drug combination may cause side effects or fail to improve outcomes.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Tangdu Hospital, Air Force Medical University, Xi'an 710038, Shaanxi Province, China
RECRUITINGShanxi, Province, China
Contact Phone: •••-•••-•••• Email: •••••@•••••