Immunotherapy combo shows promise in battling esophageal cancer before surgery

NCT ID NCT06952621

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding the immunotherapy drug toripalimab to standard chemotherapy before surgery can improve outcomes for people with resectable locally advanced esophageal squamous cell carcinoma. About 390 participants will be randomly assigned to receive either toripalimab plus nab-paclitaxel and platinum, or a standard chemo regimen (docetaxel, cisplatin, 5-fluorouracil). The main goal is to see if the new combination leads to a higher rate of complete tumor disappearance after treatment.

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Conditions

The condition(s) this trial relates to.

esophageal squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tangdu Hospitial, Xi'an, Shaanxi Rrovince

    Xi'an, Shaanxi, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact