Shanghai Ninth People's Hospital Affiliated To Shanghai Jiao Tong University

This study tests a new treatment for people with high-risk head and neck cancer who cannot receive the standard chemotherapy drug cisplatin. After surgery, patients receive radiation therapy combined with a targeted drug (nimotuzumab), followed by an immunotherapy drug (benmelsto…

This study tests three common cleaning tools—superfloss, interdental brushes, and a water flosser—on people with full-arch implant-supported dentures. Each participant will use each tool for three months to see which removes the most plaque. The goal is to find the best way to pr…

This study compares two ways to treat early gum disease (gingivitis and mild periodontitis). One group uses a smart electric toothbrush with an app, while the other adds professional dental cleaning. The goal is to see if the toothbrush alone works just as well. About 92 adults w…

This study compares two balloon treatments used after placing a stent in long blockages (over 10 cm) in the leg arteries of people with peripheral artery disease. One balloon is coated with a drug to help keep the artery open, while the other is a standard balloon. The goal is to…

This study is testing whether simpler, less invasive methods like taking mouth photos, X-rays, and analyzing spit and plaque samples can accurately detect gum disease. Researchers will compare these methods to the standard full-mouth dental exam. The goal is to find a faster, eas…

This study aims to create an artificial intelligence (AI) system that can objectively measure redness (erythema) in the gum tissue around dental implants. Currently, diagnosing this redness is subjective and varies between dentists. The AI will analyze digital scans of the mouth …

This study tests whether taking taurine granules before daily radiation can reduce painful mouth sores and skin burns in 160 oral cancer patients. Half get taurine, half get a placebo. The goal is to ease side effects and improve quality of life during treatment.

This study aims to discover biological markers that can predict which people with mild gum inflammation will develop serious gum disease. Researchers will analyze saliva, tissue, and bacteria samples from 228 adults aged 18-40 with gingivitis or early-stage periodontitis. The goa…