Could a saliva test predict gum disease before it starts?
NCT ID NCT07293481
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to find biological markers in saliva, gum fluid, and tissue that can predict which people with mild gum inflammation will develop serious periodontitis. Researchers will use advanced techniques to analyze samples from 228 adults aged 18-40 with gingivitis or early-stage periodontitis. Participants will be followed for 24 months to see if the biomarkers can accurately forecast disease progression.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a simple test to predict who will develop periodontitis, enabling early treatment and preventing tooth loss.
- What could go wrong
- This is an early discovery-phase study with no direct treatment. The biomarkers may not prove accurate enough for clinical use, and results may take years to apply.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Shanghai 9th people's hospital
RECRUITINGShanghai, Shanghai Municipality, 200120, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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