New chemo combo shows promise for tough head and neck cancers

NCT ID NCT07662746

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial is testing a special form of the chemotherapy drug paclitaxel, called polymeric micelles, combined with carboplatin in 29 people with recurrent or metastatic head and neck squamous cell carcinoma. The goal is to see how well the treatment shrinks tumors and to monitor side effects. Participants receive the drugs intravenously every three weeks, continuing as long as the cancer does not worsen and side effects are manageable.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

paclitaxel polymeric micelles (a form of chemotherapy) plus carboplatin

What this could lead to

If this works, it could offer a new chemotherapy option for people with head and neck cancer that has come back or spread.

What could go wrong

This is a small, early-phase trial with only 29 participants, so results may not apply to everyone. Chemotherapy side effects can be severe, and the treatment may not shrink tumors as hoped.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms head and neck squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • the Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

    RECRUITING

    Shanghai, Shanghai Municipality, 200011, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••