Shanghai Ninth People's Hospital Affiliated To Shanghai Jiao Tong University

This study tests whether a robot can place dental implants more accurately than a computer-guided navigation system in the front upper jaw. Twenty-four adults needing an implant will be randomly assigned to one of the two methods. The main goal is to see which approach achieves b…

This study compares a new, personalized way of giving a blood thinner (citrate) during kidney dialysis to the standard method. It involves 142 adults with acute kidney injury or advanced chronic kidney disease who also have liver failure or poor blood flow. The goal is to see if …

This phase II trial tests a combination of an antibody-drug conjugate (a targeted cancer drug) and stereotactic body radiotherapy (precise, high-dose radiation) in 40 people with recurrent or metastatic salivary gland cancer. Participants first receive the drug; if their disease …

This study tests whether adding the drug benmelstobart to standard radiotherapy and nimotuzumab can help prevent head and neck cancer from coming back after surgery. About 386 patients with intermediate-risk features will be randomly assigned to one of two groups. The main goal i…

This study tests whether a mixed reality system, similar to video game technology, can help surgeons remove oral cancer and rebuild the area more accurately. Thirty people with oral cancer will be split into three groups: one using mixed reality, one using a virtual surgical guid…

This study tests a combination of three drugs (pucotenlimab, lenvatinib, and temozolomide) given before and after surgery for people with a rare type of melanoma in the head and neck area. The goal is to see if this approach can shrink tumors and improve outcomes. About 30 adults…

This study tests whether people with advanced head and neck cancer who respond to immunotherapy can safely have a smaller, less invasive surgery than usual. The goal is to preserve organ function and quality of life without lowering the chance of survival. About 356 participants …

This study tests an artificial intelligence system called PerioAI V2.0 that creates a detailed 3D map of gum disease from dental scans. Researchers will enroll 80 adults with moderate-to-severe periodontitis who need gum surgery. The AI's map will be compared to what surgeons see…

This study will enroll 2,000 adults to see if non-invasive methods like smartphone photos, dental X-rays, and questionnaires can accurately detect gum disease compared to a standard clinical exam. Researchers will use artificial intelligence to analyze the images and combine data…

This study looks at whether using a laser to thin the outer shell of a frozen embryo (called laser-assisted hatching) can help women aged 35 and older have a baby. About 916 women will be randomly assigned to receive the laser treatment or standard care. The main goal is to see i…

This study looks at a rare type of cancer called oral mucosal melanoma. Researchers want to improve how the cancer is staged by measuring how deep it goes into tissue and by studying its genetic makeup. They will follow 1,100 patients over time to see which treatments work best f…

This study compares two high-tech methods for placing dental implants in people missing back teeth on one side of the mouth. One method uses a robotic arm to guide the dentist, while the other uses a custom-made surgical template. The goal is to see which approach places implants…

This study looks at whether transferring an embryo on day 2 or day 3 after fertilization leads to more live births in women aged 35 or older with low ovarian reserve. About 470 women will be randomly assigned to one of the two transfer times. The goal is to find out which timing …