Shanghai Ninth People's Hospital Affiliated To Shanghai Jiao Tong University

This study tests whether a combination of three drugs (pucotenlimab, lenvatinib, and temozolomide) given before and after surgery can improve outcomes for people with a rare type of melanoma in the head and neck area. The trial will enroll 30 adults whose tumors can be surgically…

This study tests whether mixed reality (MR) technology can help surgeons remove oral cancer and rebuild the mouth more precisely. Thirty adults with oral cancer will be split into three groups: one using MR goggles, one using a 3D-printed guide, and one having standard surgery. T…

This study compares a new, personalized way of giving blood-thinning medication during kidney dialysis to the standard method. It involves 142 adults with acute kidney injury or advanced chronic kidney disease who also have liver failure or poor blood flow. The goal is to see if …

This study tests a two-step treatment for people with advanced salivary gland cancer that has come back or spread. First, patients receive a targeted drug that delivers chemotherapy directly to cancer cells. Then, if the disease is stable or only a few new spots appear, they get …

This study tests whether adding the drug benmelstobart to standard radiation and nimotuzumab after surgery can help prevent head and neck cancer from returning. About 386 adults with intermediate-risk features will take part. The main goal is to see if the combination improves ho…

This study looks at whether people with advanced head and neck cancer who respond well to immunotherapy can have a smaller, less damaging surgery instead of the standard extensive surgery. The goal is to see if the smaller surgery can preserve quality of life and organ function w…

This study tests a new AI system (PerioAI V2.0) that combines 3D dental scans and X-rays to create detailed maps of gum disease. Researchers will enroll 80 adults with moderate-to-severe periodontitis to see if the AI can accurately identify bone defects and help plan surgery. Th…

This study will check if simple methods like mouth photos, dental X-rays, and health questionnaires can accurately find gum disease compared to a full dentist exam. About 2,000 adults will take part, and the results will help create AI tools for faster, easier screening. The goal…

This study looks at whether using a laser to thin the outer shell of a frozen embryo (laser-assisted hatching) can improve the chance of a live birth in women aged 35 and older. About 916 women will be randomly assigned to receive either the laser treatment or standard care durin…

This study compares the accuracy of digital scans versus traditional putty impressions for making dental implants in people with no teeth. About 24 adults aged 30-80 will receive one method and be checked over 6 visits. The goal is to see which technique gives a better fit for pe…

This study looks at whether transferring an embryo on day 2 or day 3 after fertilization leads to more live births in women aged 35 or older with low egg supply. About 470 women will be randomly assigned to one of the two transfer days. The goal is to find the best timing to impr…

This study compares two advanced methods for placing dental implants in people missing back teeth on one side: robotic-assisted surgery and static guide surgery. The goal is to see which method places implants more accurately and improves patient outcomes. About 112 adults will t…