Shanghai Mental Health Center

This study tests a non-invasive brain stimulation method called tTIS to see if it can reduce alcohol cravings and prevent relapse in people with alcohol use disorder. Sixty adults aged 18-60 who meet the criteria for alcohol use disorder will receive the stimulation targeting the…

This study tests a non-invasive brain stimulation technique called targeted temporal interference stimulation (tTIS) aimed at the caudate nucleus. The goal is to reduce drug craving and improve reward-learning behaviors in 60 adults with methamphetamine use disorder. Participants…

This study tests whether a non-invasive brain stimulation technique called tACS can help people with gambling disorder. The treatment aims to improve brain function related to self-control. Sixty adults with gambling disorder will receive either real or fake stimulation, and thei…

This study will check if an artificial intelligence (AI) system can diagnose depression as accurately as a psychiatrist. About 100 adults with depression will take part. Their diagnosis from the AI will be compared to the one from a psychiatrist to see if the AI is just as good.

This study will test whether an artificial intelligence (AI) system can diagnose anxiety disorders as accurately as a psychiatrist. One hundred adults with anxiety will be evaluated by both the AI and a specialist to compare their diagnostic accuracy. The goal is to see if AI can…

This study tests a non-drug treatment called transcranial electrical stimulation (tES) for people who have both depression and chronic pain. 240 adults will receive one of four types of brain stimulation (or a sham) for 2 weeks. Researchers will measure changes in pain and mood t…

This study tests whether adding an AI-based rehabilitation program to standard treatment helps adults with anxiety disorders more than standard treatment alone. About 158 people aged 18 to 60 will take part. The main goal is to see if anxiety symptoms improve, as measured by a st…

This early-stage study tests a nasal spray made from neural stem cell particles (exosomes) in 9 people with moderate-to-severe early-onset Alzheimer's. The main goal is to check safety and how well people tolerate different doses given over 28 days. Researchers will also look for…

This pilot study tests whether high-intensity alternating current stimulation on the scalp can reduce alcohol cravings and drinking behavior in 18 adults with alcohol use disorder. Participants receive the stimulation and report changes in cravings and drinking habits. The goal i…

This study looks at why people with OCD have strange or uncomfortable feelings before they repeat behaviors. It will use brain scans and a gentle magnetic stimulation (rTMS) to see if changing activity in a specific brain circuit can help. The study includes 120 adults with OCD a…