Shanghai Mental Health Center

This early-stage study tests whether a nasal spray containing particles from neural stem cells is safe for people with moderate-to-severe early-onset Alzheimer's. Nine participants aged 50-75 will receive different dosing schedules over 28 days. The main goal is to check for side…

This study tests a non-invasive brain stimulation technique called transcranial temporal interference stimulation (tTIS) aimed at the amygdala, a brain region linked to cravings. Researchers will enroll 60 adults with alcohol use disorder to see if tTIS can reduce alcohol craving…

This pilot study will test whether a high-intensity brain stimulation device can help people with alcohol use disorder reduce their cravings and drinking. Eighteen adults will receive 20 sessions of stimulation over 10 days. Researchers will measure changes in cravings, drinking …

This study will check if an artificial intelligence (AI) system can diagnose depression as accurately as a psychiatrist. About 100 adults with depression will take part. Their AI-based diagnosis will be compared to the diagnosis made by a mental health specialist.

This study will test whether an artificial intelligence (AI) system can diagnose anxiety disorders as accurately as a psychiatrist. One hundred adults with anxiety will be assessed by both the AI and a specialist, and the results will be compared. The goal is to see if the AI is …

This study tests whether gentle ultrasound waves aimed at the brain can help with memory and thinking problems in people with schizophrenia. 140 adults with stable schizophrenia will receive either real or fake ultrasound sessions over 20 days. Researchers will check if memory an…

This study tests whether an AI-based rehabilitation program, combined with usual care, can reduce anxiety symptoms more than usual care alone. About 158 adults with anxiety disorders will use the AI system for 12 sessions over 3 weeks. The goal is to see if digital therapy can im…

This study tests a non-drug treatment called transcranial electrical stimulation (tES) for people who have both depression and chronic pain. 240 adults will receive one of four types of brain stimulation or a fake treatment for two weeks. Researchers will check if it reduces pain…

This study looks at 130 people with major depression who have suicidal thoughts. Researchers will use brain scans, genetic tests, and other biological measures to see how rapid treatments like Esketamine and electroconvulsive therapy (ECT) change the brain. The goal is to find ea…

This study looks at how certain brain circuits cause strange sensory feelings in people with Obsessive-Compulsive Disorder (OCD). It will test if a non-invasive brain stimulation technique called rTMS can reduce these symptoms. The study involves 120 adults with OCD and healthy v…