Shock therapy without the shock? new brain zaps aim to lift mood and kill pain

NCT ID NCT07334561

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a non-drug treatment called transcranial electrical stimulation (tES) for people who have both depression and chronic pain. 240 adults will receive one of four types of brain stimulation or a fake treatment for two weeks. Researchers will check if it reduces pain and depression symptoms, and look at brain scans and blood markers to understand how it works.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Shanghai Mental Health Center

    Shanghai, Shanghai Municipality, 200030, China

  • Shanghai Tenth People's Hospital

    Shanghai, Shanghai Municipality, 200072, China

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