Royal Marsden Nhs Foundation Trust

This early-stage study is testing the safety and effectiveness of combining two drugs, palbociclib and avelumab, for patients with advanced breast cancer. It focuses on a specific, hard-to-treat type called AR-positive triple-negative breast cancer. The goal is to see if this new…

This study tests whether a digital exercise program with live virtual group sessions helps men with prostate cancer stick to regular exercise while on hormone therapy. Researchers want to see if this convenient approach overcomes common barriers like travel time and motivation, h…

This study aims to understand why head and neck cancers sometimes come back after a patient has received radiation treatment. Researchers will analyze tumor samples from before and after radiation to see how the cancer cells change and become resistant. The goal is to gather know…

This study aims to understand what happens to people who need a second surgery because their head and neck cancer has come back or didn't fully go away after initial treatment. It will track 400 patients to see how long they survive cancer-free, how the surgery affects their abil…

This study aims to understand how personalized chemotherapy before surgery works for high-risk sarcoma patients. Researchers will collect tissue samples from 800 patients who either receive chemotherapy before surgery or go directly to surgery. By analyzing these samples, they ho…

This study aims to understand why some cancer patients develop serious side effects from immunotherapy drugs called checkpoint inhibitors. Researchers will follow 200 patients with solid tumors, collecting blood and stool samples before and during treatment to look for biological…

This study aims to understand how breast cancer changes and becomes resistant to treatment by taking multiple tissue samples from different tumor sites over time. Researchers will collect biopsy samples from 200 people with metastatic breast cancer at diagnosis and when their can…