New study tracks outcomes of Second-Chance surgery for head and neck cancer
NCT ID NCT05808920
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
The RESCUE study is looking at 400 adults who have salvage surgery for head and neck cancer that came back after radiation. Researchers will track how long patients live without the cancer returning and how well they function after surgery. They will also analyze tumor tissue, blood, and saliva to explore links between genetics, past radiation, and cancer recurrence.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could help doctors better predict which patients benefit from salvage surgery and understand why cancer returns after radiotherapy.
What could go wrong
This is an observational study, not a treatment trial. It will not directly test a new therapy, and results may not change current care for years.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Aintree Hospital
RECRUITINGLiverpool, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Head and Neck Unit, Royal Marsden Hospital
RECRUITINGLondon, SW3 6JJ, United Kingdom
Contact Email: •••••@•••••
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NHS Lothian
RECRUITINGEdinburgh, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Northwick Park
RECRUITINGLondon, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Oxford University Hospital NHS Foundation Trust
RECRUITINGOxford, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Poole Hospital, University Hospitals Dorset
RECRUITINGPoole, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
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South Tyneside and Sunderland NHS Foundation Trust
COMPLETEDSunderland, United Kingdom
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University Hospitals Derby and Burton
RECRUITINGDerby, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Western General, Greater Glasgow and Clyde
RECRUITINGGlasgow, United Kingdom
Contact Phone: •••-•••-•••• Email: •••••@•••••