Royal Marsden Nhs Foundation Trust

This phase 2 study tests whether adding the experimental drug ipatasertib to standard hormone therapy and a targeted drug can help people with a specific type of advanced breast cancer (ER+/HER2-) live longer without their cancer growing. The study includes 57 participants whose …

This study looks at a new surgical method to find the original site of head and neck cancers that have spread to lymph nodes but have no known starting point. About 100 patients will have their tongue base tissue removed and examined in detail. The goal is to see if this approach…

This study follows 170 men with metastatic hormone-sensitive prostate cancer who choose to take apalutamide as part of their standard care. Researchers will measure how well the drug lowers PSA levels and how it affects fatigue, thinking skills, and overall quality of life using …