Rhode Island Hospital

This study tested whether a natural hormone called DHEA can improve heart function in people with pulmonary arterial hypertension (PAH), a condition where high blood pressure strains the heart. 26 adults took DHEA or a placebo in a crossover design, and researchers measured heart…

This study tested two different doses of praziquantel in 354 children aged 1-4 with schistosomiasis, a parasitic infection. The goal was to find the safest and most effective dose to cure the infection and improve growth and nutrition. The trial was conducted in Uganda and compar…

This study tested a program called Guardians 4 Health that teaches adults and youth in 4-H Shooting Sports Clubs how to step in and prevent firearm injuries. The goal was to change attitudes and behaviors around safe firearm storage and use. The study included 801 participants fr…

This study tested a program called iDOVE2 for teens at risk of peer violence and depression. The program started with a brief session in the emergency department, followed by automated text messages. Researchers aimed to see if this approach could reduce violent behavior and depr…

This study tested whether giving lidocaine through an IV works as well as a targeted nerve block for controlling pain after knee replacement surgery. 120 adults having a knee replacement took part. The goal was to see if the IV method could reduce the need for strong opioid paink…

This study tested if an ultrasound-guided nerve block (Serratus Anterior Plane Block) helps patients with rib fractures feel less pain and breathe easier. 40 adults with rib fractures received either the nerve block or usual care. Researchers measured pain, breathing, and cough a…

This study tested a non-drug treatment called Personalized Integrated Chronotherapy (PIC) for depression during pregnancy and after childbirth. 120 pregnant women with major depression received either usual care (medication or therapy) or PIC plus usual care. PIC combines bright …