Rhode Island Hospital

This study compares two daily doses of buprenorphine (16 mg vs. 24 mg) to see if a higher dose helps people with opioid use disorder stay in treatment longer and reduce cravings. Researchers will enroll 250 adults who have used fentanyl and are starting or continuing buprenorphin…

This study tests if a drug called treprostinil can help protect a new kidney from injury during transplant surgery. About 20 adults receiving a deceased donor kidney will get the drug through an IV for two days. The goal is to see if it improves kidney function and reduces the ne…

This study is creating and testing short videos for teens (ages 12-17) and their parents after a serious injury that requires a hospital stay. The goal is to prevent post-traumatic stress disorder (PTSD) and substance use. The videos will be developed with input from families and…

This early-phase trial tests whether taking vitamin A and nicotinamide (a form of vitamin B3) can help prevent skin cancer in kidney transplant recipients who have already had skin cancer. The study will enroll 30 adults and measure changes in blood vitamin levels to see if the s…

This study looks at whether adding dexmedetomidine to a standard numbing medicine (ropivacaine) in a nerve block can improve pain control after hip replacement surgery. About 120 adults aged 18-80 having elective hip surgery will take part. The goal is to see if the combination d…

This study tests if a small, non-invasive device that stimulates a nerve in the leg can safely and effectively relieve Restless Legs Syndrome (RLS) in pregnant women. Fifteen pregnant participants between 21 and 26 weeks will use the device for 30-minute sessions as needed over 8…

This study looks at how the amount of sleep urban children with asthma get affects their immune system and breathing. Researchers will test 204 children aged 7-11 by changing their sleep times and measuring immune markers and lung function. The goal is to understand why city kids…