Region Stockholm

This study is testing whether giving high-flow nasal oxygen right after major surgery can reduce lung complications in frail adults. About 200 high-risk patients having abdominal or chest surgery will be randomly assigned to receive either high-flow oxygen or standard oxygen. The…

This study follows 500 people with ulcerative colitis who have already tried at least two advanced medications without success. Participants choose either to continue trying different medications or to have their colon removed (colectomy). Researchers will compare quality of life…

This study tests whether dapagliflozin, a drug typically used for diabetes, can prevent atrial fibrillation from coming back after a procedure called cardioversion (an electric shock to restore normal heart rhythm). About 1600 adults with AF will take either dapagliflozin or no e…

This study uses the Swedish Heart Failure Registry to identify people with heart failure and reduced ejection fraction who may need medication adjustments, iron deficiency screening, device therapy, or physiotherapy. Researchers will compare outcomes for 500 patients who receive …

This study tests whether a new CT-angiography method can accurately diagnose brain death compared to the standard four-vessel angiography. About 50 adults with severe brain injury will receive both tests. If the CT method works as well, it could offer a faster, less invasive way …

This study tests a new way to process brain MRI scans that reduces blurring caused by breathing. Researchers will compare standard images with those corrected by the new method in 100 adult patients. The goal is to see if the correction makes scans clearer for diagnosing brain di…

This study tests a new MRI sequence that aims to make brain tumors (metastases) more visible after a standard contrast injection. Researchers will compare the new method to the usual MRI in 100 adults with known or suspected brain tumors. The goal is to see if the new scan finds …

This study tests if a 12-week cognitive behavioral therapy (CBT) program can help people with paraphilic disorders reduce problematic sexual behaviors and improve their mental health. Researchers will track daily symptoms and interview participants about their experiences. The go…

This study tests whether brief cognitive behavioral therapy (CBT) can help people hospitalized for depression or anxiety. About 204 patients will receive CBT sessions during their stay. The goal is to see if this therapy reduces symptoms and improves daily functioning.

This study compares 240 people with paraphilic disorders, compulsive sexual behavior, or sexsomnia to healthy controls. Researchers will assess violence history, psychiatric traits, and genetic factors through interviews, questionnaires, and blood samples. The clinical group will…

This study is testing whether a new genetic test (called PCAI ImmunoScore) can predict how well men with high-risk prostate cancer will respond to the drug darolutamide before surgery. About 100 participants will take darolutamide for 3-4 months, then have their prostate removed.…

This study looks at whether doctors can rely on feeling a patient's pulse (in the neck, groin, or wrist) to know if their blood pressure is dangerously low during shock. Researchers will compare pulse checks with standard blood pressure readings in 5,000 critically ill adults in …

This study looks at why sarcoidosis affects people differently—some get better, others develop long-term lung damage. Researchers will analyze genes, immune cells, and gut bacteria from 5,000 participants, including healthy volunteers. The goal is to find markers that predict dis…

This study tests whether heart failure patients can safely drink as much fluid as they want instead of restricting it. Researchers will compare lung congestion, blood markers, quality of life, and hospital readmissions in 326 participants over time. The goal is to see if liberal …

This study surveys 500 people who inject drugs and use needle exchange programs in Sweden. Researchers will ask about their experiences with physical, psychological, and sexual violence from partners. The goal is to understand how common this violence is and what support survivor…

This study observes 200 adults who had a bleeding stroke from a brain aneurysm and now have narrowed blood vessels. Researchers will monitor brain blood flow using ultrasound to see how it changes with standard treatments like raising blood pressure or using medication to widen v…

This study tests whether dynamic MRI can better track lung tumor movement during breathing compared to standard CT scans. 150 patients receiving stereotactic body radiotherapy for lung tumors will get an extra MRI scan. If MRI proves more accurate, it could help doctors plan radi…