Could a common diabetes drug keep your heart in rhythm?

NCT ID NCT07187570

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether dapagliflozin, a drug typically used for diabetes, can prevent atrial fibrillation from coming back after a procedure called cardioversion (an electric shock to restore normal heart rhythm). About 1600 adults with AF will take either dapagliflozin or no extra drug for up to 56 days. Researchers will track heart rhythm using a handheld device to see if the drug reduces recurrence.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
dapagliflozin (a diabetes drug that lowers blood sugar and may help heart rhythm)
What this could lead to
If it works, this could offer a new, short-term treatment to prevent atrial fibrillation from coming back after cardioversion.
What could go wrong
This is a phase 3 trial, but it's still early to know if dapagliflozin truly helps AF. The drug may not reduce recurrence, and side effects like dehydration or kidney issues are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Akademiska sjukhuset

    NOT_YET_RECRUITING

    Uppsala, 75389, Sweden

  • Danderyds Hospital

    NOT_YET_RECRUITING

    Stockholm, 18527, Sweden

  • Karolinska University Hospital

    RECRUITING

    Stockholm, 14186, Sweden

  • Linköping university hosptial

    NOT_YET_RECRUITING

    Linköping, 58225, Sweden

  • Norrlands universitetssjukhus

    NOT_YET_RECRUITING

    Umeå, 90185, Sweden

  • Södersjukhuset

    NOT_YET_RECRUITING

    Stockholm, 11861, Sweden

  • Örebro University hospital

    RECRUITING

    Örebro, 70382, Sweden

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