Surgery or more drugs? new study aims to guide tough UC decisions
NCT ID NCT07347834
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 500 people with ulcerative colitis who have already tried at least two advanced medications without success. Participants choose either to continue trying different medications or to have their colon removed (colectomy). Researchers will compare quality of life, bowel function, and satisfaction between the two groups over six months. The goal is to provide clearer guidance for future patients facing this difficult choice.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
advanced medical therapy (biologics or small molecules) vs. colectomy surgery
What this could lead to
If successful, this study could help doctors and patients make better-informed decisions about whether to keep trying new medications or opt for surgery after multiple treatment failures.
What could go wrong
This is an observational study, not a randomized trial, so results may be influenced by patient choice. It does not test a new drug or procedure, and outcomes depend on many individual factors.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Karolinska University Hospital
RECRUITINGSolna, Stockholm County, 17176, Sweden
Contact Phone: •••-•••-•••• Email: •••••@•••••