Poitiers University Hospital
Clinical trials sponsored by Poitiers University Hospital, explained in plain language.
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Which oxygen method saves more lives? large trial tests standard vs High-Flow
Disease control CompletedThis study tested whether giving high-flow heated oxygen through nasal prongs helps more people survive severe breathing failure than standard oxygen masks. Over 1,500 adults with low blood oxygen levels were randomly assigned to one of the two oxygen methods. The main goal was t…
Phase: NA • Sponsor: Poitiers University Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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X-rays fall short: CT scans more accurate for ARDS diagnosis, study finds
Diagnosis CompletedThis study looked at 277 ICU patients on breathing machines to see how well chest X-rays (read by intensive care doctors) agreed with CT scans (read by radiologists) for diagnosing acute respiratory distress syndrome (ARDS). The results showed only fair agreement, meaning X-rays …
Sponsor: Poitiers University Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 09:03 UTC
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Blood test may spare some stroke patients unnecessary brain scans
Diagnosis CompletedThis study tested whether a blood test measuring PS100B levels could help rule out stroke in patients with symptoms lasting more than 24 hours but less than 4 days. Researchers enrolled 179 patients at a French hospital. If the test proves accurate, it might reduce the need for e…
Sponsor: Poitiers University Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 08:08 UTC
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Blood test may spare Head-Injury patients on blood thinners from unnecessary CT scans
Diagnosis CompletedThis study tested whether measuring S100B protein levels in the blood can safely rule out serious brain injuries in adults with minor head trauma who take antiplatelet drugs (blood thinners). 720 participants had a blood test upon arriving at the emergency room, followed by a CT …
Phase: PHASE3 • Sponsor: Poitiers University Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 08:07 UTC
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Vacuum dressing may keep heart surgery scars closed
Prevention CompletedThis study tested whether using a negative pressure wound therapy (NPWT) device on the chest after heart surgery can prevent the scar from reopening, compared to a standard bandage. About 660 adults having planned or semi-urgent heart surgery through a breastbone incision took pa…
Phase: NA • Sponsor: Poitiers University Hospital • Aim: Prevention
Last updated Jun 27, 2026 08:03 UTC
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Psoriasis Drug's skin gene secrets revealed in small trial
Knowledge-focused CompletedThis study looked at how the drug adalimumab affects gene activity in the skin of people with chronic plaque psoriasis. Researchers compared skin samples from normal, non-lesional, and lesional areas before and after treatment. The goal was to understand the immune changes that h…
Phase: PHASE2 • Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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Do your diabetes sensors work when oxygen is low? new study finds out
Knowledge-focused CompletedThis study checked how well two continuous glucose monitors (Dexcom G6 and FreeStyle Libre) work when oxygen levels are low. Thirty people with type 1 or type 2 diabetes took part. Researchers compared sensor readings to blood tests during controlled low-oxygen conditions to see …
Phase: NA • Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Could eye pigment levels predict vision damage in severe nearsightedness?
Knowledge-focused CompletedThis study examined 39 people with severe nearsightedness to see if lower levels of a natural eye pigment (macular pigment) are linked to tiny cracks in the back of the eye called lacquer cracks. These cracks can lead to vision loss. The researchers measured the pigment's optical…
Phase: NA • Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Can lack of oxygen weaken your breathing muscles? new study investigates
Knowledge-focused CompletedThis study looked at whether repeated low oxygen levels, like those seen in sleep apnea, can reduce the ability to keep breathing during effort. 28 healthy volunteers did a breathing test after 6 hours of normal air and after 6 hours of low oxygen. The goal is to understand if ox…
Phase: NA • Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:04 UTC
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Scientists uncover immune cell clues in rare scleroderma
Knowledge-focused CompletedThis study looked at 235 people to understand how certain immune cells, called innate T cells, might be involved in systemic sclerosis (a rare disease that causes hardening of the skin and organs). Researchers compared patients with systemic sclerosis to those with other autoimmu…
Phase: NA • Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Can a simple sensor predict who needs a breathing tube?
Knowledge-focused CompletedThis pilot study tested a new algorithm that estimates how hard patients are working to breathe while on high-flow nasal oxygen. Researchers enrolled 20 ICU patients and used a noninvasive sensor to collect pressure and flow data. The goal was to see if the algorithm could reliab…
Phase: NA • Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:36 UTC
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New study aims to solve the mystery of persistent pain after back surgery
Knowledge-focused CompletedThis study looks at people who still have chronic back or leg pain after back surgery, a condition called Failed Back Surgery Syndrome (FBSS). Researchers want to better understand what causes this pain and how to diagnose it faster. They will collect detailed information from 20…
Phase: NA • Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Healthy volunteers help scientists map spinal fluid flow with MRI
Knowledge-focused CompletedThis study looked at how cerebrospinal fluid (CSF) moves around the brain and spinal cord in 15 healthy adults. Using special MRI scans, researchers measured fluid speeds at different points along the spine. The goal was to create a computer model that can help doctors better und…
Phase: NA • Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Brain waves may predict ventilator weaning success
Knowledge-focused CompletedThis study looked at whether measuring tiny brain signals during a breathing test can help predict if a patient on a ventilator will successfully breathe on their own. Researchers monitored 70 intubated adults as they tried breathing without the machine. The goal is to find a sim…
Phase: NA • Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Staph bacteria may worsen eczema and trigger dangerous infections
Knowledge-focused CompletedThis study looked at how staphylococcus bacteria on the skin affect inflammation and immune responses in people with moderate to severe atopic dermatitis (eczema). Researchers took skin biopsies and blood samples from 41 adults to measure bacterial toxins and immune cell activity…
Phase: NA • Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Super MRI scans hand damage in rare disease
Knowledge-focused CompletedThis study used a very powerful 7 Tesla MRI to look at the hands of 50 people with systemic sclerosis (scleroderma), a rare autoimmune disease. The goal was to see bone, joint, and blood vessel problems in detail. Researchers hope this will help them understand how the disease af…
Phase: NA • Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Heart reflex test may forecast AFib ablation success
Knowledge-focused CompletedThis study looked at 116 people with paroxysmal atrial fibrillation (AFib) who were scheduled for a heart ablation procedure. Researchers measured baroreflex sensitivity—a non-invasive test of the autonomic nervous system—before the procedure. They wanted to see if this measureme…
Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Nurse-Led care in ERs: a game changer for patient satisfaction?
Knowledge-focused CompletedThis study from a French hospital examines whether adding advanced practice nurses to the emergency department improves patient satisfaction and care quality. Researchers surveyed over 900 patients and compared data before and after the nurses started. The goal is to see if these…
Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Rehab for lungs and heart: a new hope for COPD patients with high blood pressure in the lungs?
Knowledge-focused CompletedThis study reviewed medical records of 59 adults with COPD to see if a standard pulmonary rehabilitation program is safe and effective for those who also have pulmonary hypertension (high blood pressure in the lungs). Researchers compared how much walking distance improved in peo…
Sponsor: Poitiers University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC