Ohsu Knight Cancer Institute
Clinical trials sponsored by Ohsu Knight Cancer Institute, explained in plain language.
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Cancer clock: does morning or afternoon treatment work better?
Disease control Not yet recruitingThis study is testing whether the time of day a standard immunotherapy treatment is given affects how well it works for people with advanced solid tumors. Researchers want to see if a patient's internal body clock influences the treatment's effectiveness. About 160 participants w…
Phase: PHASE2 • Sponsor: OHSU Knight Cancer Institute • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Radioactive 'Tumor Hunter' drug tested in advanced breast cancer patients
Disease control Not yet recruitingThis study is testing a new, targeted radioactive drug called 177Lu-DOTATATE in patients with advanced breast cancer that has spread or returned. The drug is designed to seek out and attach to specific cancer cells, delivering radiation directly to the tumor to try to shrink it a…
Phase: PHASE2 • Sponsor: OHSU Knight Cancer Institute • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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Radical surgery offers hope for debilitating pancreas pain
Disease control Not yet recruitingThis study is testing a two-part surgery for people with severe, long-term pancreas inflammation (chronic pancreatitis) and non-cancerous tumors. First, the entire pancreas is removed to stop the pain. Then, the patient's own insulin-producing cells are collected and transplanted…
Phase: PHASE1, PHASE2 • Sponsor: OHSU Knight Cancer Institute • Aim: Disease control
Last updated Mar 16, 2026 15:26 UTC
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Could a simple pill make mammograms more accurate?
Diagnosis Not yet recruitingThis study is testing whether taking a short course of a hormone-modifying drug (ulipristal acetate) before a mammogram can temporarily reduce breast density. Dense breast tissue can hide cancer on a mammogram, making screening less effective. The goal is to see if this drug can …
Phase: PHASE2 • Sponsor: OHSU Knight Cancer Institute • Aim: Diagnosis
Last updated Mar 23, 2026 15:18 UTC
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Could teamwork exercise ease the burden of brain cancer?
Symptom relief Not yet recruitingThis study is testing a new exercise program designed for people with primary brain tumors and the family members who care for them. The program involves patients and caregivers doing supervised, virtual strength training exercises together twice a week for 12 weeks. Researchers …
Phase: NA • Sponsor: OHSU Knight Cancer Institute • Aim: Symptom relief
Last updated Mar 30, 2026 14:28 UTC