Ohsu Knight Cancer Institute

This study tests a four-drug combination for people with advanced liver cancer that cannot be surgically removed. The treatment includes radioactive beads injected into the liver, two immunotherapy drugs that boost the immune system, and a pill that blocks cancer growth. The goal…

This early-phase study tests whether giving ruxolitinib followed by ruxolitinib plus azacitidine after a stem cell transplant is safe for adults with acute myeloid leukemia (AML). The goal is to prevent graft-versus-host disease (a common transplant complication) and delay or sto…

This study tests a drug called 177Lu-DOTATATE in 10 people with stage IV or recurrent breast cancer. The drug targets cancer cells that have a specific marker (SSTR2) and delivers radiation to kill them. The goal is to see if it can shrink tumors and control the disease. Particip…

This early-phase trial tests whether removing the entire pancreas and transplanting the patient's own insulin-making cells into the liver is safe and effective for people with non-cancerous pancreatic tumors and long-term pancreatitis. The goal is to treat pain and prevent diabet…

This study tests whether taking a medication called ulipristal acetate before a mammogram can temporarily reduce breast density in premenopausal women with extremely dense breasts. Dense tissue can hide cancers on mammograms, so lowering density might improve detection. About 26 …

This study tests whether a single dose of gruticibart can prevent blood clots that often form when a catheter is placed in a large vein. About 90 adults who need a catheter will receive the drug and be monitored for clots and bleeding. The goal is to reduce pain and swelling whil…

This study tests a supervised exercise program called Exercise Together for people with primary brain tumors and their caregivers. The program uses partner exercises to improve daily functioning and strengthen the patient-caregiver relationship. Researchers want to see if the pro…