Ohsu Knight Cancer Institute
Clinical trials sponsored by Ohsu Knight Cancer Institute, explained in plain language.
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New drug cocktail shows promise in shrinking breast tumors before surgery
Disease control CompletedThis early-phase study tested two drugs, abemaciclib and niraparib, given together before surgery in 8 people with hormone receptor-positive, HER2-negative breast cancer. The goal was to find the best dose and see if the combination could shrink tumors safely. The study focused o…
Phase: PHASE1 • Sponsor: OHSU Knight Cancer Institute • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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New program aims to ease pain for head and neck cancer survivors
Symptom relief CompletedThis study tested a better pain management program for people who finished treatment for head and neck cancer. 33 survivors with ongoing pain took part. The goal was to see if the program could improve their daily physical function, mood, and overall quality of life.
Phase: NA • Sponsor: OHSU Knight Cancer Institute • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Walking before surgery may speed recovery for head and neck cancer patients
Symptom relief CompletedThis study tested whether a pre-surgery exercise program (walking, sit-to-stand, and other exercises) could help people recover mobility and avoid complications after head and neck cancer surgery. 52 adults scheduled for major surgery wore Fitbits and either did the exercises or …
Phase: NA • Sponsor: OHSU Knight Cancer Institute • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Could a simple MRI replace costly PET scans for brain tumors?
Knowledge-focused CompletedThis study tested a new way of analyzing MRI scans, called activity MRI (aMRI), to see if it can measure brain tumor activity as well as PET scans. Four adults with glioma had both aMRI and standard PET imaging. The goal was to check if aMRI results match PET findings, which coul…
Sponsor: OHSU Knight Cancer Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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Forest in a bottle: scented oils may boost immunity after cancer treatment
Knowledge-focused CompletedThis study tested whether breathing in humidified wood or fragrant oils could mimic the immune-boosting effects of a forest walk. 28 adults who finished chemotherapy or radiation for early-stage breast or prostate cancer took part. The goal was to see if this approach is practica…
Phase: NA • Sponsor: OHSU Knight Cancer Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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Smart socks and activity trackers used to predict chemo side effects
Knowledge-focused CompletedThis completed study enrolled 200 cancer patients aged 40-85 who were about to start chemotherapy. Researchers tracked symptoms like numbness, daily activity, and falls using surveys, activity monitors, and even smart socks. The goal was to find simple ways for doctors to predict…
Sponsor: OHSU Knight Cancer Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC
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Doctor training boosts skin cancer detection
Knowledge-focused CompletedThis study looked at whether a special training program could help primary care doctors better spot and treat early-stage skin cancer, especially melanoma. Fifty-four doctors from two clinics took part. The training aimed to improve their knowledge and skills in identifying suspi…
Phase: NA • Sponsor: OHSU Knight Cancer Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC