Could a simple MRI replace costly PET scans for brain tumors?

NCT ID NCT05937776

Completed Knowledge-focused Sponsor: OHSU Knight Cancer Institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new way of analyzing MRI scans, called activity MRI (aMRI), to see if it can measure brain tumor activity as well as PET scans. Four adults with glioma had both aMRI and standard PET imaging. The goal was to check if aMRI results match PET findings, which could make metabolic imaging cheaper and more widely available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, aMRI could offer a more accessible and less expensive way to monitor brain tumor activity without radioactive tracers.
What could go wrong: This is a very small, early observational study with only 4 participants. The new MRI method may not match PET accuracy and needs much larger validation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

glioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GLIOMA

Contacts and locations

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Locations

OHSU Knight Cancer Institute

Portland, Oregon, 97239, United States

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