Can a pill clear the fog on mammograms? new trial hopes so

NCT ID NCT07434128

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This phase II trial tests whether taking ulipristal acetate before a mammogram can temporarily reduce breast density in premenopausal people with extremely dense breast tissue. Dense tissue can hide cancers on mammograms, so lowering density may improve screening accuracy. The study will enroll 26 participants and compare breast density changes from their baseline mammogram to one after taking the drug.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ulipristal acetate

What this could lead to

If it works, this could make mammograms more accurate for people with dense breasts, potentially catching cancer earlier.

What could go wrong

This is a small early-phase trial with only 26 participants, so results may not apply widely. The drug only temporarily lowers breast density and may not improve cancer detection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • OHSU Knight Cancer Institute

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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