Can a pill clear the fog on mammograms? new trial hopes so
NCT ID NCT07434128
First seen Jun 24, 2026 · Last updated Aug 13, 2026 · Updated 4 times
Summary
This phase II trial tests whether taking ulipristal acetate before a mammogram can temporarily reduce breast density in premenopausal people with extremely dense breast tissue. Dense tissue can hide cancers on mammograms, so lowering density may improve screening accuracy. The study will enroll 26 participants and compare breast density changes from their baseline mammogram to one after taking the drug.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ulipristal acetate
- What this could lead to
- If it works, this could make mammograms more accurate for people with dense breasts, potentially catching cancer earlier.
- What could go wrong
- This is a small early-phase trial with only 26 participants, so results may not apply widely. The drug only temporarily lowers breast density and may not improve cancer detection.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
OHSU Knight Cancer Institute
Portland, Oregon, 97239, United States
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