New York State Psychiatric Institute

This study is testing whether improving sleep can help protect memory and thinking skills in older adults who have early signs of memory loss and trouble sleeping. Researchers will compare two different sleep treatments: talk therapy for insomnia and a headband that plays gentle …

This study tests whether treating opioid addiction through video calls works as well as traditional in-person clinic visits. 50 people with opioid addiction will receive buprenorphine medication either through telemedicine or at a clinic for 12 weeks. Researchers will compare how…

This study tests two approaches to help adults with obsessive-compulsive disorder (OCD) find and keep jobs. All 40 participants will receive standard OCD therapy, then half will get enhanced job placement support while the other half gets standard vocational services. Researchers…

This study aims to understand how psychosis develops by looking at brain chemistry in young adults who are at high risk for the condition. Researchers will use special brain scans (PET and MRI) to measure dopamine, a brain chemical linked to psychosis, in 115 participants aged 18…

This study aims to understand how the medication cariprazine (Vraylar) helps people with bipolar depression. Eight adults with the condition will take the drug and have special brain scans (PET scans) before and during treatment. Researchers will look at how the drug interacts wi…

This study aims to understand how an experimental drug called Cobenfy affects brain chemistry in people with schizophrenia. Twelve participants will receive one of three doses for five weeks and undergo special brain scans before and after treatment. The main goal is to measure i…

This study aims to understand how the drug ketamine might help reduce suicidal thoughts in people with major depression. Researchers will use smartphone apps to track daily stress and brain scans to see how ketamine affects specific brain pathways. The goal is to learn more about…