New York State Psychiatric Institute

This study tested a web-based addiction treatment program that was culturally adapted for American Indians and Alaska Natives. 53 adults in outpatient treatment used the program for 12 weeks. The goal was to see if it helped them stay away from drugs and alcohol and to decide if …

This study tested whether the antiviral drug valacyclovir (Valtrex) could slow brain changes linked to Alzheimer's in 50 people with mild cognitive impairment who also had herpes simplex virus antibodies. Participants took either valacyclovir or a placebo for 52 weeks. The goal w…

This study tests whether a mindfulness app called Headspace can help low-income parents reduce stress, anxiety, and depression. Participants use the app on their own schedule for guided meditations. Researchers measure changes in stress and mood over time to see if the app provid…

This study tested whether interpersonal psychotherapy (IPT) works as well as two established treatments for chronic post-traumatic stress disorder (PTSD): prolonged exposure therapy and relaxation therapy. 110 adults with chronic PTSD took part, receiving weekly sessions over 14 …

This study tested whether ketamine, a drug that blocks certain brain signals, can help people with tinnitus (ringing in the ears). 42 adults with chronic tinnitus received both ketamine and a placebo on different days. Researchers used brain scans to measure changes in brain chem…

This study tested whether blocking a nerve cluster called the SPG can reduce withdrawal symptoms in people with opioid use disorder. Only 3 people took part, and the goal was to see if the approach is safe and worth studying further. It did not provide addiction treatment or medi…

This study tests a tool called the Cultural Formulation Interview-Engagement Aid (CFI-EA), designed to help clinicians and patients from different cultural backgrounds communicate better. The goal is to see if using this tool improves patient satisfaction and keeps people in trea…

This study tested a program designed to make medication for opioid use disorder more culturally appropriate for American Indian and Alaska Native communities. Researchers worked with four healthcare sites to help them better support patients starting and staying on these medicati…

This study tested two methods to encourage COVID-19 testing among people who use opioids: having friends refer others (chain referral) and using trusted community members (credible messengers). About 500 people took part. The goal was to see which method got more people tested an…

This study looked at why Interpersonal Psychotherapy (IPT) helps people with PTSD. Unlike most PTSD therapies, IPT does not involve re-living traumatic memories. Instead, it focuses on improving relationships and emotional awareness. Researchers measured emotional awareness in 29…

This study tested whether a mobile app (mSBIRT) helps community health workers in Mozambique better identify and counsel people who drink too much. Over 500 health workers took part, comparing the app to standard training. The goal was to see if the app makes it easier and cheape…

This study looked at how to make mental health care more available in Sub-Saharan Africa. Researchers worked with 901 clinic staff in Mozambique to train local health workers and use existing community programs. The goal was to find cost-effective ways to help more people get the…