National Institute On Alcohol Abuse And Alcoholism (niaaa)
Clinical trials sponsored by National Institute On Alcohol Abuse And Alcoholism (niaaa), explained in plain language.
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Cholesterol drug tested to protect livers from alcohol damage
Disease control Recruiting nowThis early-stage study is testing whether a cholesterol-lowering drug called alirocumab is safe and well-tolerated in adults who are heavy drinkers. Researchers also want to see if the drug can reduce signs of liver inflammation and damage caused by alcohol. The study involves 10…
Phase: PHASE1 • Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA) • Aim: Disease control
Last updated Mar 30, 2026 14:28 UTC
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Massive NIH study tracks thousands to unlock secrets of alcohol use disorder
Knowledge-focused Recruiting nowThis study aims to better understand alcohol use problems by observing a large group of people over time. It will enroll up to 7,500 adults, including those with alcohol problems (whether they want treatment or not) and healthy volunteers. Researchers will collect detailed health…
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA) • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Could your diet soda change how your medicine works?
Knowledge-focused Recruiting nowThis study aims to find out if consuming the artificial sweetener sucralose changes how the body absorbs and processes certain medications. Researchers are enrolling 150 overweight or obese Black and Hispanic women to take either sucralose or a placebo pill for a month. They will…
Phase: PHASE2 • Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA) • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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Scientists scan brains to unlock alcohol addiction mysteries
Knowledge-focused Recruiting nowThis study aims to develop and test simple computer tasks that can be used during brain scans to better understand how alcohol use disorders affect behavior, thinking, and decision-making. Researchers are recruiting 400 adults, including both healthy volunteers and people with al…
Phase: NA • Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA) • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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Scientists scan brains to see how Anti-Craving drug works
Knowledge-focused Recruiting nowThis study aims to understand how an existing medication for alcohol use disorder (acamprosate) affects brain function. Researchers will measure brain activity using EEG caps in 48 adults with moderate to severe alcohol use disorder. Half will receive the real medication and half…
Phase: PHASE4 • Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA) • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Scientists probe gene link to drinking behavior
Knowledge-focused Recruiting nowThis study aims to understand why some people might be more vulnerable to developing alcohol problems by looking at a specific gene called ZIP8. Healthy volunteers who drink alcohol but do not have an alcohol use disorder will receive controlled alcohol infusions and have their b…
Phase: PHASE1 • Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA) • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC
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Scientists probe gene link to Alcohol's 'Buzz'
Knowledge-focused Recruiting nowThis study aims to understand how a specific gene related to nicotine receptors influences a person's brain activity and behavior when exposed to alcohol. Researchers will recruit 128 healthy adults, including both smokers and non-smokers, to undergo brain scans and controlled al…
Phase: PHASE1 • Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA) • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC
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Scientists scan brains to unlock Alcoholism's secrets
Knowledge-focused Recruiting nowThis study aims to understand how alcohol use disorder changes the brain. Researchers will use MRI brain scans and computer games to compare brain structure and function in adults with and without alcohol dependence. The goal is to link these brain differences to behavior, person…
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA) • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC
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Scientists scan healthy brains to crack Addiction's code
Knowledge-focused Recruiting nowThis research aims to develop better brain scanning methods to study how addiction affects the brain. Healthy adult volunteers will undergo MRI scans while performing simple tasks to help researchers measure brain activity and structure. The goal is to create improved tools for f…
Phase: NA • Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA) • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC
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Scientists investigate why alcohol changes how we taste and smell
Knowledge-focused Recruiting nowThis study aims to understand how alcohol use disorder affects people's senses of taste and smell. Researchers will compare 475 adults with and without alcohol use disorder through taste tests, smell assessments, brain scans, and sample collection. The goal is to identify biologi…
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA) • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Scientists track pandemic drinking: how has stress changed our habits?
Knowledge-focused Recruiting nowThis study aims to understand how the stress and isolation of the COVID-19 pandemic have affected people's alcohol use and related problems over time. Researchers will follow 1,500 participants for two years, asking them to complete regular surveys about their drinking, stress le…
Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA) • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:14 UTC
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Can a pill for sleep help rewire the addicted brain?
Knowledge-focused Recruiting nowThis study is investigating whether suvorexant, a medication approved for sleep problems, can change brain chemistry related to addiction in people with alcohol use disorder (AUD). Researchers will compare brain scans, sleep patterns, and cravings in people with AUD receiving eit…
Phase: PHASE1, PHASE2 • Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA) • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:40 UTC