Could a Weight-Loss drug curb alcohol cravings? new brain study investigates

NCT ID NCT07559500

First seen Jun 27, 2026 · Last updated Jul 29, 2026 · Updated 3 times

Summary

This study looks at whether tirzepatide, a drug used for diabetes and weight loss, can change how the brain responds to alcohol-related cues in people with alcohol use disorder (AUD). Researchers will use brain scans to measure dopamine activity in healthy volunteers and people with AUD after taking tirzepatide or a placebo. The goal is to understand how the drug affects brain chemistry, not to treat the disorder directly.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

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