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Could a Weight-Loss drug curb alcohol cravings? new brain study investigates

NCT ID NCT07559500

Recruiting now Knowledge-focused Sponsor: National Institute on Alcohol Abuse and Alcoholism (NIAAA) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether tirzepatide, a drug used for diabetes and weight loss, can change how the brain responds to alcohol-related cues in people with alcohol use disorder (AUD). Researchers will use brain scans to measure dopamine activity in healthy volunteers and people with AUD after taking tirzepatide or a placebo. The goal is to understand how the drug affects brain chemistry, not to treat the disorder directly.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

alcohol abuse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALCOHOL USE DISORDER (AUD)

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••