Could your sense of taste and smell be driving obesity?

NCT ID NCT04714892

First seen Jul 20, 2026 · Last updated Jul 23, 2026 · Updated 3 times

Summary

This study investigates whether differences in taste and smell perceptions affect food choices and eating behaviors in people with and without obesity. Researchers will compare measures of taste, smell, and eating habits between the two groups, along with genetic, inflammatory, and microbiome data. The goal is to understand how these senses may contribute to obesity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could explain why some people with obesity have different taste and smell perceptions, potentially pointing toward new ways to help manage weight.
What could go wrong
This is an observational study, not a treatment trial, so it will not directly test any therapy. Results may not lead to immediate practical changes.

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Conditions

The condition(s) this trial relates to.

Anosmia Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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