National Health Research Institutes, Taiwan

This study tests whether a strict lifestyle program—eating only during an 8-hour window, walking 10,000 steps daily, and cutting 500 calories—can help obese adults with metabolic syndrome lose weight and improve heart health. After 24 weeks, participants also receive either Rybel…

This study is for people with advanced stomach cancer that has spread and who have already tried one type of treatment. It tests a combination of three drugs (ramucirumab, nal-IRI, and trifluridine/tipiracil) to see if they can shrink tumors and help patients live longer. The stu…

This study tests a combination of two drugs—cabozantinib (a daily pill) and lanreotide (a monthly injection)—in people with advanced gastroenteropancreatic neuroendocrine tumors (GEP-NETs) that have stopped responding to prior treatments. The trial has two phases: the first finds…

This Phase 2 trial tests whether a chemotherapy drug called pegylated liposomal doxorubicin (PLD) can help people with advanced soft tissue sarcoma live longer without their cancer growing. Participants who have already responded to standard chemotherapy will either receive PLD e…

This study looks at whether a 16-week program combining mindfulness meditation and Nordic walking pole exercise can improve physical function, mood, and sleep in adults aged 55 and older. About 1,500 participants will take part in the program and be assessed at several points. Th…

This study is testing whether a special vibration device, used along with standard rehab, can improve muscle strength, movement, and pain in older adults and stroke survivors. About 80 participants will receive either vibration therapy plus rehab or rehab alone. The goal is to se…

This study looks at whether different exercise programs can improve blood flow in the legs of older adults with poor circulation. About 425 participants will be split into groups doing either mixed exercise, high-intensity rowing, or vibration exercise for 12 weeks. The goal is t…

This study tests whether mindfulness programs or a brain stimulation device can improve mood and thinking in older adults with depression. Researchers will track brain activity and well-being over time. The goal is to find safe, non-drug ways to help seniors feel better.

This study is building a computer model to predict chronic disease risk in adults. Researchers will collect data from 1,500 people in Taiwan using smartwatches (for heart rate and activity), hearing tests, questionnaires, and medical records. The goal is to see if combining these…

This study aims to collect and analyze genetic information from 300 Taiwanese women with ovarian cancer. Researchers will look at tumor samples and medical records to find gene changes linked to treatment response and survival. The goal is to build a database that helps develop p…

This study is following 5,000 middle-aged and older adults in Taiwan who are Tzu Chi volunteers and eat plant-based or vegetarian diets. Researchers want to see if these diets are linked to healthier aging, including better memory, stronger muscles, and lower risk of frailty. Par…

This study aims to understand the genetic makeup of non-small-cell lung cancer in 550 Taiwanese patients, especially those whose tumors are resistant to standard treatments. By analyzing tumor samples, researchers hope to find new drug targets and improve survival. Participants a…

This study aims to collect and analyze genetic information from 300 Taiwanese patients with oropharyngeal cancer. Researchers will use advanced DNA sequencing to find genetic changes linked to the disease. The goal is to improve understanding and help design future treatments or …

This study aims to collect and analyze genetic information from 250 adults in Taiwan diagnosed with diffuse gliomas, a type of brain tumor. Researchers will use tumor tissue and blood samples to identify genetic patterns. The goal is to better understand why these tumors are so h…