Can mindfulness or brain zaps lift Late-Life depression?

NCT ID NCT07186023

Recruiting now Symptom relief Sponsor: National Health Research Institutes, Taiwan Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether mindfulness programs or a brain stimulation device can improve mood and thinking in older adults with depression. Researchers will track brain activity and well-being over time. The goal is to find safe, non-drug ways to help seniors feel better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: mindfulness-based programs and brain stimulation device
What this could lead to: If successful, this could point toward effective non-drug treatments for depression in older adults, improving mental health without medication.
What could go wrong: This is an early-stage study with only 124 participants, so results may not apply to everyone. The interventions require time and commitment, and brain changes may not translate to lasting symptom relief.

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Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRAIN STIMULATION INTERVENTION LATE LIFE DEPRESSION LATE-LIFE ADULTS LATE-LIFE PRODROMAL DEPRESSION MINDFULNESS

Contacts and locations

Locations

National Center for Geriatrics and Welfare Research
NOT_YET_RECRUITING

Yunlin, 632007, Taiwan
Shuang Ho Biomedical Park, Taipei Medical University
RECRUITING

New Taipei City, 235603, Taiwan

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